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## Cholecystokinin - **Molecular form** - 8-AA, 33-AA, 38-AA, 59-AA - Synthesized as preprohormone, then cleaved to form a family of peptides - 5 C-terminal AA identical to gastrin - **Biological activity** - Minimal active fragment - 7 C-terminal AA - Tyrosine, 7 residues from C-t...

## Cholecystokinin - **Molecular form** - 8-AA, 33-AA, 38-AA, 59-AA - Synthesized as preprohormone, then cleaved to form a family of peptides - 5 C-terminal AA identical to gastrin - **Biological activity** - Minimal active fragment - 7 C-terminal AA - Tyrosine, 7 residues from C-terminal must be sulfated for full activity at physiological levels - Produces all effects of gastrin at high doses.