From Blood Filtrate to Urine: A Closer Look PDF
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Uploaded by MesmerizedMoldavite7389
ANTH/LING
2021
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This document provides a detailed explanation of the process of urine formation, specifically examining the roles of the proximal tubule, loop of Henle (descending and ascending limbs), distal tubule, and collecting duct. It emphasizes the active and passive transport mechanisms involved in the process. Copyright © 2021 Pearson Education Ltd.
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From Blood Filtrate to Urine: A Closer Look (혈액 여과액에서 소변이 되기까지) Proximal tubule (근위세뇨관) • Reabsorption (재흡수) of ions, water, and nutrients takes place in the proximal tubule (이온, 수분 및 영양소의 재흡수는 근위 세뇨관에서 이루어짐) • Molecules are transported actively and pass...
From Blood Filtrate to Urine: A Closer Look (혈액 여과액에서 소변이 되기까지) Proximal tubule (근위세뇨관) • Reabsorption (재흡수) of ions, water, and nutrients takes place in the proximal tubule (이온, 수분 및 영양소의 재흡수는 근위 세뇨관에서 이루어짐) • Molecules are transported actively and passively from the filtrate into the interstitial fluid and then capillaries (분자는 여과액에서 간질액으로, 그리고 모세혈관으로 능동적 및 수동적으로 운반됨) • Some toxic materials are actively secreted into the filtrate (일부 독성 물질은 여과액으로 활발하게 분비됨) Descending limb of the loop of Henle (헨레고리의 하행지) • Reabsorption of water continues through channels formed by aquaporin (아쿠라포린) proteins (아쿠아포린 단백질에 의해 형성된 채널을 통해 수분 재흡수가 계속된다) • The filtrate becomes increasingly concentrated all along its journey down the descending limb (여과액은 하강하는 가지를 따라 이동하는 동안 점점 더 농축) Copyright © 2021 Pearson Education Ltd. All Rights Reserved From Blood Filtrate to Urine: A Closer Look (혈액 여과액에서 소변이 되기까지) Ascending limb of the loop of Henle (헨레고리의 상행지) • The ascending limb has a transport epithelium that lacks water channels (상행지에는 물 채널이 없는 수송 상피가 있다) • Here, salt but not water is able to move from the tubule into the interstitial fluid (여기서 물은 아니지만 Na+는 세뇨관에서 간질액으로 이동할 수 있다) • The filtrate becomes increasingly dilute as it moves up to the cortex (여과액은 피질로 올라갈수록 점점 더 희석됨) Copyright © 2021 Pearson Education Ltd. All Rights Reserved Animation: Loop of Henle Copyright © 2021 Pearson Education Ltd. All Rights Reserved From Blood Filtrate to Urine: A Closer Look (혈액 여과액에서 소변이 되기까지) Distal tubule (원위세뇨관) • The distal tubule regulates the K + and NaCl concentrations of body fluids by varying the amount of K+ secreted into the filtrate and NaCl reabsorbed from the filtrate (원위세뇨관은 여과액으로 분비되는 K+ 양과 NaCl 재흡수를 조절하여 간질액의 K+와 NaCl 농도를 조절함) • The controlled movement of ions contributes to pH regulation (이온의 제어된 이동은 pH 조절에 기여함) Copyright © 2021 Pearson Education Ltd. All Rights Reserved From Blood Filtrate to Urine: A Closer Look (혈액 여과액에서 소변이 되기까지) Collecting duct (집합관) • The collecting duct carries filtrate to the renal pelvis (집합관은 여과액을 신장 골반으로 운반함) • As filtrate passes along the transport epithelium of the collecting duct, regulation of permeability and transport across the epithelium determines the concentration of the urine (여과액이 집합관의 수송 상피를 따라 통과할 때 상피를 통한 투과성 및 수송 조절에 따라 소변의 농도가 결정됨) Copyright © 2021 Pearson Education Ltd. All Rights Reserved
