photo.jpg

## Satiety - Hypothalamic centers - **Satiety center:** inhibits appetite and is located in the ventromedial nucleus of the hypothalamus - **Feeding center:** stimulates appetite and is located in the lateral hypothalamic area of the hypothalamus. - Anorexigenic neurons release proopiomela...

## Satiety - Hypothalamic centers - **Satiety center:** inhibits appetite and is located in the ventromedial nucleus of the hypothalamus - **Feeding center:** stimulates appetite and is located in the lateral hypothalamic area of the hypothalamus. - Anorexigenic neurons release proopiomelanocortin (POMC) in the hypothalamic centers and cause decreased appetite. - Orexigenic neurons release neuropeptide Y in the hypothalamic centers and stimulate appetite. - Leptin is secreted by fat cells. It stimulates anorexigenic neurons and inhibits orexigenic neurons, thus decreasing appetite. - Insulin and GLP-1 inhibit appetite. - Ghrelin is secreted by gastric cells. It stimulates orexigenic neurons and inhibits anorexigenic neurons, thus increasing appetite. Peptide YY inhibits ghrelin secretion and thus decreases appetite.