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### **Antidote: 72-hour N-acetylcysteine (NAC) protocol** - 140 mg/kg initially and 70 mg/kg every 4 hours for 17 more doses (orally or IV). - Children >40 kg IV administration of 150mg/kg over 1 hour, diluted in 500 mL D% followed by maintenance dose of 100 mg/kg over 16 hours in 1000 mL D5W. - S...
### **Antidote: 72-hour N-acetylcysteine (NAC) protocol** - 140 mg/kg initially and 70 mg/kg every 4 hours for 17 more doses (orally or IV). - Children >40 kg IV administration of 150mg/kg over 1 hour, diluted in 500 mL D% followed by maintenance dose of 100 mg/kg over 16 hours in 1000 mL D5W. - Supportive therapy. - The antidote is most effective ≤8 hours of ingestion but decreases hepatotoxicity even >24 hours.
