Skin & Soft Tissue Diseases - Dermatitis, Eczema, Urticaria, Psoriasis

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18 Questions

What is the pathogenesis of Psoriasis mainly characterized by?

Secretion of cytokines and growth factors by CD8+ T cells

Which factor is NOT mentioned as a trigger for the appearance of Psoriasis?

Myopathy

What is the characteristic morphological change seen in the skin surface of patients with Psoriasis?

Roughening due to abnormal scale formation and shedding

Which statement accurately describes the clinical features of Psoriasis?

Psoriasis is a chronic inflammatory dermatosis

Which of the following is NOT associated with Psoriasis according to the text?

Dilated lymphatic and blood-filled vascular spaces

How are psoriatic lesions induced in susceptible individuals by local trauma known as?

Koebner phenomenon

What is the main characteristic of acute dermatitis?

Formation of vesicles in the epidermis

Which of the following best describes the pathogenesis of acute dermatitis?

Inflammatory cells infiltrating around blood vessels

What is a common morphological change seen in acute dermatitis?

Swelling of the upper dermis

Which clinical feature is typically associated with acute dermatitis?

Redness, tenderness, and itching

In Psoriasis, what are some of the known causes?

Genetic factors

Which best describes a common morphological change in Psoriasis?

Thickening and scaling of the skin

What is a common characteristic of all forms of eczema?

Oozing and crusted lesions

Which skin condition most commonly affects the hands?

Eczema

What is the term used to describe a thin-walled sac filled with fluid in dermatology?

Vesicle

Which skin condition is likely caused by a fungus in the oil glands?

Seborrheic Dermatitis

What is reactive acanthosis and hyperkeratosis in eczema a result of?

Chronic inflammation

Which term describes a solid or cystic raised spot on the skin that is less than 1 centimeter wide?

Papule

Study Notes

Psoriasis

  • Mainly characterized by an abnormal immune response that leads to rapid proliferation of skin cells
  • Triggered by factors such as genetic predisposition, environmental factors, and other medical conditions
  • NOT triggered by trauma

Morphological Changes

  • Characteristic morphological change in Psoriasis: thickening of the epidermis (hyperkeratosis) and an increased number of skin cells (acanthosis)
  • In acute dermatitis: spongiosis (intercellular edema) and exocytosis (leukocyte migration into the epidermis)

Clinical Features

  • Psoriasis: characterized by scaly, erythematous plaques and papules
  • Acute dermatitis: characterized by erythema, edema, and vesiculation
  • Eczema: characterized by dry, scaly, and itchy skin

Lesions and Triggers

  • Psoriatic lesions induced in susceptible individuals by local trauma known as Köbner phenomenon
  • Acute dermatitis triggered by external factors such as allergens, irritants, and infections

Other Skin Conditions

  • Eczema: a common morphological change is spongiosis and exocytosis
  • Fungal skin condition: likely caused by a fungus in the oil glands, such as in acne
  • Reactive acanthosis and hyperkeratosis in eczema result from an abnormal immune response
  • Vesicle: a thin-walled sac filled with fluid in dermatology
  • Papule: a solid or cystic raised spot on the skin that is less than 1 centimeter wide

Learn about dermatitis, eczema, urticaria, and psoriasis - their causes, pathogenesis, morphological changes, and clinical features. Specific learning outcomes include detailed descriptions of each skin condition.

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