PMLS 01: Laboratory Biosafety and Biosecurity Basics

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What is the primary purpose of laboratory biosafety?

To prevent unintentional exposure to pathogens and toxins

Which concept is related to the protection of valuable biological materials within laboratories?

Biosecurity

What was the purpose of terminating the biological weapons program by US President Richard Nixon in 1969?

To end the biological weapons program

What is the main focus of laboratory biosecurity?

Preventing unauthorized access and intentional release of biological materials

Which category does the classification of microorganisms according to their risk group fall under?

Laboratory biosafety

What is the purpose of biosafety level classification of laboratories?

To prevent unintentional exposure to pathogens and toxins

Who was the first scientific director of Camp Detrick (Fort Detrick)?

Ira L. Baldwin

When was the American Biological Safety Association (ABSA) formed?

1967

Where are the only two locations where the variola virus is officially stored?

CDC and VECTOR

Which organization published the NIH Guidelines for Research Involving Recombinant DNA Molecules?

NIH

Who is recognized as one of the pioneers of biosafety?

Arnold Wedum

What event took place in 2001 involving Bacillus anthracis spores?

Amerithrax incident

What did the World Health Assembly agree to do regarding stocks of variola virus?

Reduce the number of laboratories holding stocks

Who analyzed multiple epidemiological studies of laboratory-based outbreaks along with Arnold Wedum?

Morton Reitman

What was the purpose of Ira L. Baldwin's establishment of US biological weapons program for defensive purposes during the Cold War?

To develop a defensive biological weapons program

Study Notes

Laboratory Biosafety and Biosecurity

  • The primary purpose of laboratory biosafety is to protect laboratory workers, the environment, and the public from exposure to infectious agents.

Protection of Biological Materials

  • The concept of "biological select agents" is related to the protection of valuable biological materials within laboratories.

Biological Weapons Program

  • In 1969, US President Richard Nixon terminated the biological weapons program to prevent the development of biological weapons for offensive purposes.

Laboratory Biosecurity

  • The main focus of laboratory biosecurity is to prevent the misuse of biological agents and toxins that could be used as biological weapons.

Classification of Microorganisms

  • The classification of microorganisms according to their risk group falls under the category of biosafety levels.

Biosafety Level Classification

  • The purpose of biosafety level classification of laboratories is to ensure that laboratories handling infectious agents have the necessary safety protocols and facilities in place.

History of Biosafety

  • The first scientific director of Camp Detrick (Fort Detrick) was Ira L. Baldwin.
  • The American Biological Safety Association (ABSA) was formed in 1984.
  • Robert K. Johannes was recognized as one of the pioneers of biosafety.

Variola Virus

  • The variola virus is officially stored only in two locations: the Centers for Disease Control and Prevention (CDC) in Atlanta, Georgia, and the State Research Center of Virology and Biotechnology in Koltsovo, Russia.

NIH Guidelines

  • The National Institutes of Health (NIH) published the NIH Guidelines for Research Involving Recombinant DNA Molecules.

Epidemiological Studies

  • Arnold Wedum and his team analyzed multiple epidemiological studies of laboratory-based outbreaks.

Anthrax Attacks

  • In 2001, letters containing Bacillus anthracis spores were mailed, resulting in several deaths and a significant public health response.

World Health Assembly

  • The World Health Assembly agreed to destroy all remaining stocks of variola virus by 2002.

Test your knowledge on the basic concepts of laboratory biosafety and biosecurity, including the history, policies, fundamental concepts, and classification of microorganisms. This quiz is designed to help students understand the related policies, guidelines, and organizations governing laboratory biosafety and biosecurity.

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