Hemostasis and Coagulation Pathways

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What is the main goal of the coagulation phase of hemostasis?

To convert fibrinogen into fibrin.

In hemostasis, what is the role of thrombin?

To activate prothrombinase.

During clot retraction in hemostasis, what happens as the fibrin network grows?

Blood cells and platelets are trapped in the fibrous tangle.

What is the role of endothelins released by endothelial cells in hemostasis?

Stimulate smooth muscle contraction

During the platelet phase of hemostasis, what is the function of von Willebrand factor?

Stimulates platelet adhesion to exposed surfaces

What is the primary purpose of activated platelets in the coagulation process?

Release clotting compounds that initiate fibrin formation

During the vascular phase of hemostasis, what is the main function of the endothelial cells?

Contraction and exposure of basement membrane

Which of the following is NOT a function of platelets in the hemostasis process?

Produce antibodies

What is the main role of thrombin in the coagulation phase of hemostasis?

Breaks down fibrinogen into fibrin

Which phase of hemostasis involves the contraction of smooth muscle fibers in the vessel wall and lasts for about 30 minutes?

Vascular phase

Learn about the process of hemostasis, including platelet aggregation, platelet plug formation, and the coagulation phase involving the extrinsic, intrinsic, and common pathways. Explore the release of chemicals, platelet adhesion to damaged vessels, and the formation of a fibrin mesh.

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