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26 Questions

What is the time required for microbial cells to double in number?

What protein binds to the origin of replication (oriC) and initiates bidirectional DNA synthesis in bacteria?

What prevents additional rounds of replication by blocking DnaA from binding to the oriC region?

What do fast-growing cells with generation times less than the replication time contain?

What is the major shape-determining factor in bacteria?

What is the function of the Par system and PopZ in bacteria?

What is the role of Min proteins in bacterial cell division?

What is a major feature of cell division in bacteria?

What is the function of bactoprenol in bacterial cell division?

What triggers biofilm formation in Vibrio cholerae?

What is the role of cyclic di-GMP signaling in biofilm formation?

What is the function of Fts proteins in bacterial cell division?

What is the function of PopZ in bacterial cell division?

What is the function of the divisome in bacterial cell division?

What is the role of SEDS proteins in bacterial cell division?

What is the function of Pseudomonas aeruginosa polysaccharides in biofilm formation?

What is the mechanism of action of Daptomycin?

Which antibiotic binds to pentapeptide precursor and prevents interbridge formation?

What are the genetically encoded classes of antibiotic resistance mechanisms?

What is the function of efflux pumps in antibiotic resistance?

What makes the antibiotic target no longer essential in antibiotic resistance?

What is the role of persisters in antibiotic resistance?

What do toxin-antitoxin (TA) modules encode?

What does HipA do in the stringent response pathway?

What induces the stringent response pathway?

What allows persisters to exit the stringent response pathway?

Summary

Bacterial Cell Division, Morphology, Biofilm Formation, and Antibiotic Targets

  • Chromosome segregation is necessary for distributing chromosomes and plasmids equally to daughter cells and for septum formation
  • Bacteria use the Par system and PopZ to distribute chromosomes and plasmids equally
  • The divisome, made up of Fts proteins, is essential for binary fission and involves the synthesis of new cytoplasmic membrane and cell wall material
  • Min proteins ensure the divisome forms at the center of the cell and prevent the FtsZ ring from forming elsewhere
  • Bacteria contain shape-determining proteins such as MreB and SEDS proteins
  • MreB is the major shape-determining factor in bacteria and recruits other proteins involved in cell wall growth
  • Bacterial cell morphologies vary, and morphology is typically unrelated to phylogeny
  • Peptidoglycan biosynthesis is a major feature of cell division, and bactoprenol carries peptidoglycan precursors through the cytoplasmic membrane
  • Biofilm formation involves initial attachment, cyclic di-GMP signaling, and gene expression for intercellular communication and extracellular polysaccharides
  • Pseudomonas aeruginosa forms a tenacious biofilm with polysaccharides that increase pathogenicity and prevent antibiotic penetration
  • Vibrio cholerae biofilm formation is triggered by low cell densities and repressed by high densities, and is more likely to occur in natural marine environments
  • Antibiotics target essential molecular processes such as DNA replication, RNA synthesis, translation, and protein synthesis, and some target specific bacterial structures and enzymes, like DNA gyrase, topoisomerase IV, and RNA polymerase

Description

Test your knowledge of bacterial cell division, morphology, biofilm formation, and antibiotic targets with this quiz. From chromosome segregation to biofilm formation and antibiotic resistance mechanisms, this quiz covers essential concepts in bacterial biology.

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