Anti-anginal Drugs & Mechanisms Quiz

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10 Questions

What is the primary cause of angina pectoris?

Insufficient coronary blood flow

Which risk factor is NOT associated with angina?

Regular physical activity

What type of angina is associated with atheromatous plaques that partially occlude one or more coronary arteries?

Atherosclerotic angina

What type of pain is characteristic of atherosclerotic angina?

Sudden, severe, crushing chest pain radiating to the neck, jaw, back, and arms

What percentage of angina cases does atherosclerotic angina constitute?


What is the main cause of vasospastic angina?

Reversible spasm of coronaries

Which of the following is NOT a pharmacologic therapy for angina?

Platelet aggregation inhibitors

What is the primary role of nitric oxide (NO) in the cardiovascular system?

Mediate relaxation of the corpus cavernosum

What was prescribed to Alfred Nobel to ease his chest pain when he developed angina in 1890?

Glyceryl trinitrate (nitroglycerin)

Why should nitroglycerin tablets be kept in tightly closed glass containers?

To avoid plastic surface adsorption

Study Notes

Angina Pectoris

  • Primary cause of angina pectoris: reduction in blood flow to the heart muscle due to coronary artery disease

Risk Factors

  • NOT associated with angina: unknown

Types of Angina

  • Atherosclerotic angina: associated with atheromatous plaques that partially occlude one or more coronary arteries
  • Characteristic pain of atherosclerotic angina: squeezing, pressure, or tightness in the chest, arm, or jaw
  • Atherosclerotic angina constitutes: approximately 90% of angina cases

Vasospastic Angina

  • Main cause: coronary artery spasm
  • Pain pattern: recurrent episodes of chest pain at rest, often during the night or early morning hours

Pharmacologic Therapy for Angina

  • NOT a pharmacologic therapy for angina: antibiotics

Nitric Oxide (NO)

  • Primary role in the cardiovascular system: vasodilation, reducing blood pressure

Historical Note

  • Alfred Nobel's treatment for angina in 1890: nitroglycerin


  • Storage requirements: tightly closed glass containers to prevent degradation by moisture and light

Test your knowledge of anti-anginal drugs and their mechanisms with this quiz. Explore topics such as organic nitrates, β-blockers, calcium channel blockers, and other medications used to treat angina.

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