Which of the followings can not act as a chemical buffer at physiological pH?

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Understand the Problem

The question is asking which of the listed substances cannot function as a chemical buffer at physiological pH. This involves understanding the buffering properties of various compounds.

Answer

Acetic acid/acetate

The final answer is E) Acetic acid/acetate, as it does not typically buffer at physiological pH.

Answer for screen readers

The final answer is E) Acetic acid/acetate, as it does not typically buffer at physiological pH.

More Information

Acetic acid/acetate does not work effectively at physiological pH (around 7.4) because its buffering range is closer to its pKa of about 4.76.

Tips

Ensure the buffer system matches the relevant physiological pH range for effectiveness.

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