Which of the following antibodies will most likely confirm the diagnosis?
Understand the Problem
The question presents a clinical case of a 40-year-old woman with symptoms suggestive of an autoimmune condition. It asks which antibody test result would most likely confirm the diagnosis, referencing a specific laboratory finding of antinuclear antibodies (ANA). The user needs to identify the most relevant antibody among the provided options.
Answer
Anti-Smith (SM)
The final answer is A. Anti-Smith (SM).
Answer for screen readers
The final answer is A. Anti-Smith (SM).
More Information
Anti-Smith antibodies are highly specific to systemic lupus erythematosus (SLE), helping to confirm the diagnosis when clinical symptoms suggest the disease.
Tips
Remember that while anti-Smith is specific for SLE, anti-double stranded DNA antibodies are more commonly used for disease activity monitoring rather than initial diagnosis confirmation.
Sources
- Antinuclear Antibodies (ANA) - American College of Rheumatology - rheumatology.org
- Lupus Blood Tests - hopkinslupus.org
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