Which histone modification is associated with the opening of chromatin?
Understand the Problem
The question is asking which histone modification is linked to the opening of chromatin, implying a focus on the regulation of gene expression through epigenetic mechanisms.
Answer
Histone acetylation
The final answer is histone acetylation.
Answer for screen readers
The final answer is histone acetylation.
More Information
Histone acetylation decreases the positive charge on histones, reducing their affinity for negatively charged DNA, thus leading to a more open chromatin structure and facilitating transcription.
Tips
A common mistake is confusing histone acetylation with histone methylation, which can either repress or activate transcription, depending on the context.
Sources
- Histone Modification - News-Medical - news-medical.net
- Histone modifications - Abcam - abcam.com
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