Which class of calcium channel blockers works on both cardiac and smooth muscle cells?
Understand the Problem
The question is asking which class of calcium channel blockers is effective in both cardiac and smooth muscle cells. The options provided are different classifications of calcium channel blockers, and the goal is to identify the correct one based on their physiological effects.
Answer
Non-dihydropyridine calcium channel blockers.
Non-dihydropyridine calcium channel blockers work on both cardiac and smooth muscle cells.
Answer for screen readers
Non-dihydropyridine calcium channel blockers work on both cardiac and smooth muscle cells.
More Information
Non-dihydropyridines, such as verapamil and diltiazem, directly affect cardiac conduction, making them useful in treating conditions like arrhythmias, in addition to their effects on smooth muscle cells.
Tips
A common mistake is confusing dihydropyridine and non-dihydropyridine blockers. Dihydropyridines primarily target vascular smooth muscle and are less effective on cardiac muscle.
Sources
- Calcium Channel Blockers - StatPearls - NCBI Bookshelf - ncbi.nlm.nih.gov
- Calcium Channel Blockers - PMC - NCBI - ncbi.nlm.nih.gov
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