What were the contributions of Levene in the discovery of DNA components in 1910?
Understand the Problem
The question is referring to the discovery of DNA components by Levene in 1910 and mentioning nucleotide and tetranucleotide concepts, likely seeking historical context or details about his contributions to molecular biology.
Answer
Levene proposed the tetranucleotide hypothesis, identifying DNA as composed of equal nucleotides.
Phoebus Levene proposed the tetranucleotide hypothesis, suggesting DNA was composed of equal parts adenine, guanine, cytosine, and thymine. Although incorrect about its structural repetition, his work helped identify nucleotides as DNA components and influenced further research, such as Chargaff's rules.
Answer for screen readers
Phoebus Levene proposed the tetranucleotide hypothesis, suggesting DNA was composed of equal parts adenine, guanine, cytosine, and thymine. Although incorrect about its structural repetition, his work helped identify nucleotides as DNA components and influenced further research, such as Chargaff's rules.
More Information
Levene's work laid foundational understanding of DNA's chemical nature. Though his hypothesis was eventually disproved, it spurred future research crucial to the discovery of DNA's true structure and function.
Tips
Common mistakes involve confusing the tetranucleotide hypothesis with correct DNA sequence organization. Clarify that Chargaff's rules later corrected this misunderstanding.
Sources
- Phoebus Levene - DNA from the Beginning - dnaftb.org
- Phoebus Levene | Discoveries & Biography - Britannica - britannica.com
- The other discoverers of DNA - aaas.org
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