What role does asparagine play in the formation of oxaloacetate?
Understand the Problem
The question is discussing the biochemical process involving asparagine and asparaginase, particularly how asparagine is converted into aspartate, which then forms oxaloacetate. This relates to metabolic pathways and the role of these compounds in supporting cellular functions, especially in the context of leukemia treatment.
Answer
Asparagine converts to aspartate, which forms oxaloacetate.
Asparagine is hydrolyzed by asparaginase to produce aspartate. Aspartate then undergoes transamination to form oxaloacetate.
Answer for screen readers
Asparagine is hydrolyzed by asparaginase to produce aspartate. Aspartate then undergoes transamination to form oxaloacetate.
More Information
Asparagine can be hydrolyzed to aspartate, a precursor for oxaloacetate in the citric acid cycle, through a transamination reaction.
Tips
Ensure understanding of enzyme-catalyzed reactions and the role of transamination in amino acid conversion.
Sources
- AMINO ACIDS | Specific Functions - sciencedirect.com
- Asparagine - Wikipedia - en.wikipedia.org
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