What is the role of CD8+ T cells in response to HIV infection?
Understand the Problem
The question is asking about the specific function of CD8+ T cells in the context of HIV infection, particularly how these cells respond to and manage the effects of the virus.
Answer
CD8+ T cells kill HIV-infected cells and control viral replication.
CD8+ T cells play a crucial role in the immune response to HIV infection by recognizing and lysing HIV-infected cells. They maintain long-term memory and effector potential, essential in controlling viral replication, especially during acute and early stages of infection.
Answer for screen readers
CD8+ T cells play a crucial role in the immune response to HIV infection by recognizing and lysing HIV-infected cells. They maintain long-term memory and effector potential, essential in controlling viral replication, especially during acute and early stages of infection.
More Information
CD8+ T cells, also known as cytotoxic T lymphocytes, play an essential role in recognizing and destroying cells that harbor viruses, thereby controlling viral infections like HIV. Their ability to maintain memory and effector functions is critical in long-term viral suppression strategies.
Tips
A common mistake is assuming that CD8+ T cells alone can completely eradicate HIV; however, the virus can evade immune responses, so therapeutic interventions are often necessary.
Sources
- CD8+ T-cell function and response to HIV infection - PubMed - pubmed.ncbi.nlm.nih.gov
- The role of CD8 T cells in controlling HIV beyond the antigen - onlinelibrary.wiley.com
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