What is the primary effect of increased arterial blood pressure (ABP) on cerebral blood flow (CBF) during autoregulation?
Understand the Problem
The question is asking about the physiological response of cerebral blood flow to changes in arterial blood pressure, specifically within the context of autoregulation. The user wants to understand how increased arterial blood pressure affects cerebral blood flow.
Answer
CBF increases with increased ABP above the autoregulatory limits.
The primary effect of increased arterial blood pressure (ABP) on cerebral blood flow (CBF) during autoregulation is an increase in CBF above the upper limit of autoregulation.
Answer for screen readers
The primary effect of increased arterial blood pressure (ABP) on cerebral blood flow (CBF) during autoregulation is an increase in CBF above the upper limit of autoregulation.
More Information
Under normal autoregulatory conditions, cerebral blood flow (CBF) is maintained constant despite changes in arterial blood pressure (ABP). However, if the ABP becomes too high and surpasses the upper limit of autoregulation, the CBF will increase. This can expose the cerebral vessels to potentially harmful shear stress.
Tips
A common mistake is to assume that any increase in ABP will automatically lead to increased CBF, without considering the range of autoregulation.
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