What distinguishes tissue stem cells from committed progenitor cells?
Understand the Problem
The question is asking about the differences between tissue stem cells and committed progenitor cells, focusing on their characteristics such as self-renewal, potential to differentiate, and division rates.
Answer
Progenitor cells have limited replication and differentiation capacity while stem cells can replicate indefinitely.
Progenitor cells differ from tissue stem cells in that they have a limited ability to replicate and restricted differentiation capacity. Stem cells can replicate indefinitely and maintain an undifferentiated state, while progenitor cells have a limited replication capacity and further differentiate into specific cell types.
Answer for screen readers
Progenitor cells differ from tissue stem cells in that they have a limited ability to replicate and restricted differentiation capacity. Stem cells can replicate indefinitely and maintain an undifferentiated state, while progenitor cells have a limited replication capacity and further differentiate into specific cell types.
More Information
Tissue stem cells maintain the ability to remain undifferentiated while progenitor cells are on a path to becoming specialized cells, which limits their potential for self-renewal.
Tips
It is a common mistake to confuse progenitor cells for stem cells due to their shared ability to differentiate. However, their replication capacity is notably different.
Sources
- Progenitor cell - Wikipedia - en.wikipedia.org
- Tissue-Derived Stem and Progenitor Cells - PMC - NCBI - ncbi.nlm.nih.gov
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