What are the standards and testing methods for Paracetamol Syrup?
Understand the Problem
The text provides detailed standards and methods for testing the identification, quality, and components of Paracetamol Syrup. It outlines various methods for ensuring its proper composition and purity through specific procedures.
Answer
Standards: 95.0%-105.0% paracetamol; Tests: TLC, HPLC, assays.
The standards for Paracetamol Syrup include a content range of 95.0% to 105.0% of paracetamol. Testing methods involve thin-layer chromatography for identification, high-performance liquid chromatography for 4-aminophenol, and specific assays with sulphuric acid and ferric ammonium sulphate. Loss on drying should not exceed 0.5%.
Answer for screen readers
The standards for Paracetamol Syrup include a content range of 95.0% to 105.0% of paracetamol. Testing methods involve thin-layer chromatography for identification, high-performance liquid chromatography for 4-aminophenol, and specific assays with sulphuric acid and ferric ammonium sulphate. Loss on drying should not exceed 0.5%.
More Information
Ensuring the correct concentration and purity of paracetamol in syrup form is crucial for efficacy and safety. Various chromatographic techniques help in precise identification and quantification.
Tips
Ensure accurate preparation and calibration of solutions when performing chromatographic methods.
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