Match the gene associated with antibiotic resistance: VRSA | B-lactamase Clindamycin | mecA gene ESBL | Erm gene Oxacillin | Cefoxitin
Understand the Problem
The question is asking to match specific types of antibiotic resistance genes or mechanisms with the respective associated antibiotics or resistance profiles. It highlights some key bacteria and antibiotics involved in antibiotic resistance.
Answer
1. VRSA - VanA gene 2. B-lactamase - ESBL 3. Clindamycin - Erm gene 4. Oxacillin/Cefoxitin - mecA gene
- VRSA - VanA gene 2. B-lactamase - ESBL 3. Clindamycin - Erm gene 4. Oxacillin/Cefoxitin - mecA gene
Answer for screen readers
- VRSA - VanA gene 2. B-lactamase - ESBL 3. Clindamycin - Erm gene 4. Oxacillin/Cefoxitin - mecA gene
More Information
Here's how the resistance genes match with the antibiotics: Vancomycin resistance in Staphylococcus aureus (VRSA) is often associated with the VanA gene. Extended Spectrum B-Lactamases (ESBL) confer b-lactamase activity. The Erm gene is responsible for clindamycin resistance. The mecA gene is associated with methicillin resistance, including resistance to oxacillin and cefoxitin.
Tips
A common mistake would be to confuse ESBL with a specific gene for a single antibiotic when it is actually a group of enzymes that confer resistance across many beta-lactam antibiotics.
Sources
- Antimicrobial resistance markers distribution in Staphylococcus ... - bmcinfectdis.biomedcentral.com
- Molecular Mechanisms of Drug Resistance in Staphylococcus aureus - mdpi.com
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