Is PLO an organogel?
Understand the Problem
The question is asking whether PLO (Phospholipid/Poloxamer gel) is classified as an organogel, which refers to a gel formed by trapping a liquid organic phase within a network of a solid phase.
Answer
Yes, PLO is an organogel.
PLO is considered an organogel, specifically a lecithin-based organogel, used to enhance the transdermal permeability of drugs.
Answer for screen readers
PLO is considered an organogel, specifically a lecithin-based organogel, used to enhance the transdermal permeability of drugs.
More Information
Pluronic Lecithin Organogel (PLO) is a widely used compounding agent in pharmacies to enhance the delivery of medications through the skin. It consists of lecithin and Pluronic F-127, creating a versatile transdermal vehicle.
Tips
A common misunderstanding is the nature of PLO as an organogel, since the term may imply that it is entirely organic. However, PLOs are lecithin-based, enabling them to act as effective transdermal delivery agents.
Sources
- Pluronic lecithin organogel (PLO) and its uses - pubmed.ncbi.nlm.nih.gov
- Explore PLO Gels - Enclara Pharmacia - enclarapharmacia.com
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