In which scenario would antibody transfer from donor to recipient cause significant hemolysis? A) When the recipient is experiencing a bacterial infection at the time. B) When the... In which scenario would antibody transfer from donor to recipient cause significant hemolysis? A) When the recipient is experiencing a bacterial infection at the time. B) When the donor has a different blood type than the recipient. C) If the donor's antibodies are in high enough quantity. D) If the recipient has existing antibodies against donor antigens.
Understand the Problem
The question is asking in what situation the transfer of antibodies from a donor to a recipient would lead to significant destruction of red blood cells (hemolysis). This involves understanding blood types, transfusion reactions, and the immune response.
Answer
When the donor has a different blood type than the recipient.
The significant hemolysis would occur when the donor has a different blood type than the recipient.
Answer for screen readers
The significant hemolysis would occur when the donor has a different blood type than the recipient.
More Information
Hemolysis in a transfusion occurs when there is an incompatibility between the donor's and recipient's blood types, often due to ABO or Rh factor mismatch which leads to the recipient's immune system attacking the transfused blood cells.
Tips
A common mistake is assuming that the quantity of antibodies alone is responsible for hemolysis without considering the compatibility of blood types.
Sources
- Risk factors for hemolytic transfusion reactions resulting from ABO ... - sciencedirect.com
- Hemolytic Transfusion Reactions - PMC - PubMed Central - pmc.ncbi.nlm.nih.gov
AI-generated content may contain errors. Please verify critical information
