If the oxyhemoglobin dissociation curve shifts to the right, the hemoglobin will only be about 75 percent saturated with oxygen as it leaves the alveoli—despite the fact that the p... If the oxyhemoglobin dissociation curve shifts to the right, the hemoglobin will only be about 75 percent saturated with oxygen as it leaves the alveoli—despite the fact that the patient's plasma PO2 is still 60 mm Hg.
Understand the Problem
The question pertains to the oxygen-hemoglobin dissociation curve, specifically discussing the implications of a rightward shift in the curve on hemoglobin saturation levels. It is likely focused on physiological concepts related to oxygen transport in the blood.
Answer
Right shift decreases oxygen affinity, reducing saturation at given PO2.
The shift to the right indicates decreased hemoglobin affinity for oxygen, causing lower saturation levels at a given PO2. This means hemoglobin is less saturated with oxygen despite a plasma PO2 of 60 mm Hg.
Answer for screen readers
The shift to the right indicates decreased hemoglobin affinity for oxygen, causing lower saturation levels at a given PO2. This means hemoglobin is less saturated with oxygen despite a plasma PO2 of 60 mm Hg.
More Information
A rightward shift often occurs in conditions such as increased temperature, high CO2 levels, or acidosis, facilitating oxygen release to tissues.
Tips
A common mistake is thinking a right shift increases saturation. Remember, a right shift decreases affinity, promoting oxygen release.
Sources
- Physiology, Oxygen Transport And Carbon Dioxide Dissociation Curve - ncbi.nlm.nih.gov
- Oxygen–hemoglobin dissociation curve - Wikipedia - en.wikipedia.org
