How might this change affect the structure and function of the protein?
Understand the Problem
The question is asking how a mutation in a polypeptide chain, specifically the substitution of cysteine with valine, might affect the structure and function of a protein. It requires analysis of the effects of this change on the protein's folding and its overall functionality.
Answer
The protein may misfold and not function properly due to the different chemical properties of valine compared to cysteine.
The final answer is that the R-group of the new amino acid, valine, has different chemical properties than the R-group of cysteine. This will cause the protein to misfold and not function properly in the cell.
Answer for screen readers
The final answer is that the R-group of the new amino acid, valine, has different chemical properties than the R-group of cysteine. This will cause the protein to misfold and not function properly in the cell.
More Information
Proteins need specific shapes to function correctly. The R-group or side chain differences, especially in charge or polarity, can greatly affect protein folding and therefore its activity.
Tips
Ensure you consider the chemical nature of amino acid side chains, as they are crucial to protein structure.
Sources
- Unit 1 MQR - Quizlet - quizlet.com
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