How does muscle tissue contribute to glycemic control?
Understand the Problem
The question is asking about the role of muscle tissue in glycemic control, specifically how it affects blood glucose levels among the provided options.
Answer
Muscle tissue aids glycemic control via insulin-dependent and independent glucose uptake, and exercise enhances this.
Muscle tissue contributes to glycemic control by facilitating glucose uptake, primarily through insulin-dependent and independent mechanisms. Skeletal muscle plays a significant role in disposing glucose, being responsible for a substantial portion of glucose uptake post-meal. Exercise also enhances this function by promoting insulin sensitivity.
Answer for screen readers
Muscle tissue contributes to glycemic control by facilitating glucose uptake, primarily through insulin-dependent and independent mechanisms. Skeletal muscle plays a significant role in disposing glucose, being responsible for a substantial portion of glucose uptake post-meal. Exercise also enhances this function by promoting insulin sensitivity.
More Information
Skeletal muscle is the largest tissue contributor to glucose homeostasis, primarily influencing postprandial glucose levels. This tissue's effectiveness is enhanced by its microvascular adaptations and increased glucose transporter type 4 (GLUT4) expression following exercise.
Tips
A common mistake is to not recognize the role of non-insulin dependent pathways in glucose uptake during exercise.
Sources
- Role of Skeletal Muscle in Insulin Resistance and Glucose Uptake - pmc.ncbi.nlm.nih.gov
- Genes controlling skeletal muscle glucose uptake - onlinelibrary.wiley.com
- Skeletal Muscle Microvascular-Linked Improvements in Glycemic Control - diabetesjournals.org
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