BEYOND FOAD: THE ADVANCED FETAL PROGRAMMING HYPOTHESIS - Proposes an additional non-environmentally driven mechanism for epigenetic modification of an offspring’s genome, impacting... BEYOND FOAD: THE ADVANCED FETAL PROGRAMMING HYPOTHESIS - Proposes an additional non-environmentally driven mechanism for epigenetic modification of an offspring’s genome, impacting the resulting phenotype. Maternal and also paternal genes may influence the maturating sperm, oocyte, embryo/fetus, leading to epigenetic alteration. Highlight the biological, psychological, and social determinants of disease across the entire life-span that can modify the effects of intrauterine exposures.
Understand the Problem
The text is a comprehensive overview of the effects of prenatal and early life environmental factors on health and development, including physical and mental health issues. It highlights the fetal programming hypothesis, the role of teratogens, and the impact of maternal and paternal genetics. The importance of caregiver responses and the biopsychosocial model are also emphasized. This material seems to be intended as lecture notes or academic content.
Answer
Parental genes may lead to epigenetic changes affecting offspring phenotype, influenced by biological, psychological, and social factors across the lifespan.
The advanced fetal programming hypothesis suggests that genes from both parents can lead to epigenetic modifications in their offspring without environmental input. Biological (genetic factors), psychological (stress, mental health), and social determinants (socioeconomic status) can influence disease by modifying these genetic expressions throughout life.
Answer for screen readers
The advanced fetal programming hypothesis suggests that genes from both parents can lead to epigenetic modifications in their offspring without environmental input. Biological (genetic factors), psychological (stress, mental health), and social determinants (socioeconomic status) can influence disease by modifying these genetic expressions throughout life.
More Information
The advanced fetal programming hypothesis extends beyond traditional environmental factors and emphasizes the role of genetic and epigenetic influences from both parents in shaping the developmental outcomes of their offspring.
Tips
A common mistake is assuming that the advanced fetal programming hypothesis is purely environmentally driven. Recognize the significance of genetic contributions from both maternal and paternal lines.
Sources
- than genes: the advanced fetal programming hypothesis - PubMed - pubmed.ncbi.nlm.nih.gov
- More than genes: The advanced fetal programming hypothesis - researchgate.net
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