A colorblind male marries a normal female. What are the offspring genotypes and phenotypes?
Understand the Problem
The question is asking about the genetic outcomes for the offspring of a colorblind male and a normal vision female. Specifically, it seeks to determine both the genotypes and phenotypes of their children based on the inheritance patterns of colorblindness, which is a sex-linked trait.
Answer
50% normal vision carrier females (X₁Xᶜ) and 50% normal vision males (X₁Y).
Answer for screen readers
The genotypes of the offspring are:
- 50% X₁Xᶜ (normal vision, carrier female)
- 50% X₁Y (normal vision male)
Steps to Solve
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Identify the genotypes
Colorblindness is a sex-linked recessive trait carried on the X chromosome. The notation we'll use is:
- Normal vision female: X₁X₁ (where X₁ represents the normal vision allele)
- Colorblind male: XᶜY (where Xᶜ represents the colorblind allele)
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Set up the Punnett square
A Punnett square can help us visualize the potential genotypes of their offspring. We'll place the mother's alleles on one side and the father's on the other.
Mother (X₁X₁)
Father (XᶜY)
The Punnett square will look like this:
X₁ X₁
----------------
Xᶜ | X₁Xᶜ | X₁Xᶜ |
Y | X₁Y | X₁Y |
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Fill in the Punnett square
Now we'll fill in the genotypes:
- X₁Xᶜ (carrier female, not colorblind)
- X₁Y (normal vision male)
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Determine phenotypes
From the completed Punnett square, we can derive the phenotypes:
- X₁Xᶜ: normal vision (carrier, female)
- X₁Y: normal vision (male)
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Calculate the ratios
Now, we can summarize the ratios from the Punnett square:
- 2 normal vision females (X₁Xᶜ)
- 2 normal vision males (X₁Y)
The offspring's expected ratio is:
- 50% normal vision females
- 50% normal vision males
The genotypes of the offspring are:
- 50% X₁Xᶜ (normal vision, carrier female)
- 50% X₁Y (normal vision male)
More Information
In sex-linked inheritance, it is important to remember that males inherit their X chromosome from their mother and the Y chromosome from their father. This is why a mother plays a crucial role in passing colorblindness to male offspring.
Tips
- Not realizing that males get their X chromosome from their mother, leading to confusion about which parent contributes the trait.
- Forgetting to consider carriers in the genotype, which can lead to incorrect phenotype ratios.
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