A 27-year-old Caucasian female with no previously known medical history presents to her family doctor for evaluation of new skin findings on her back and chest. She notes that thes... A 27-year-old Caucasian female with no previously known medical history presents to her family doctor for evaluation of new skin findings on her back and chest. She notes that these lesions are slightly raised and highly pruritic (itchy), and that they began this morning when she put on her shirt. She was concerned about the possibility of bug bites initially, but noted that 4 days ago, she tried to switch to a more floral detergent. Given this history, which of the following is most likely present in terms of pathophysiologic manifestations?
Understand the Problem
The question is asking for the pathophysiological manifestation related to a female patient's new skin findings, which have raised, itchy lesions. Given her recent switch to a floral detergent, the question presents several possible immunological responses that may be relevant.
Answer
Type I Hypersensitivity based response.
Type I Hypersensitivity based response characterized by hyper-proliferation of IgE-secreting B cells.
Answer for screen readers
Type I Hypersensitivity based response characterized by hyper-proliferation of IgE-secreting B cells.
More Information
The symptoms are consistent with allergic contact dermatitis caused by a recent change in laundry detergent. This is typically a Type I Hypersensitivity reaction, which involves an IgE-mediated response.
Tips
Be sure to consider recent changes in products or environment when diagnosing skin reactions.
Sources
- Dermatitis - Symptoms and causes - Mayo Clinic - mayoclinic.org
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