COPY: Adrenal Gland Pt 2 Quiz
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Questions and Answers

What is the primary mechanism by which cortisol increases glucose levels?

  • Increasing glucose absorption in the intestines
  • Increasing gluconeogenesis and glycogenolysis (correct)
  • Increasing insulin secretion
  • Increasing glycogenesis

How does cortisol antagonize the effects of insulin on glucose metabolism?

  • By enhancing insulin's effects on glucose metabolism
  • By increasing glucose uptake in peripheral tissues
  • By stimulating insulin secretion
  • By inhibiting insulin's inhibitory effects on gluconeogenesis and glycogenolysis (correct)

What is the primary substrate used for gluconeogenesis under the influence of cortisol?

  • Glycogen and Glycerol
  • Glucose and Amino Acids
  • Ketones and Glycerol
  • Amino acids and Glycerol (correct)

How does cortisol impact the immune system?

<p>Cortisol stabilizes lysosomal membranes and decreases the release of proteolytic enzymes by damaged cells (B)</p> Signup and view all the answers

What is the effect of cortisol on the reproductive system?

<p>Cortisol inhibits various mechanisms of action, causing a decline in reproductive success (C)</p> Signup and view all the answers

How does cortisol impact the cardiovascular system?

<p>Cortisol increases vascular smooth muscle sensitivity to vasoconstrictors and helps maintain blood pressure (A)</p> Signup and view all the answers

What is the impact of cortisol on growth?

<p>Cortisol inhibits various mechanisms of action, causing inhibition of insulin-like growth factors (IGF-1) (B)</p> Signup and view all the answers

What is the significance of the zona reticularis in the adrenal gland?

<p>The zona reticularis produces androgens, which are not significant in most animals (C)</p> Signup and view all the answers

Which receptor is responsible for vasoconstriction and increased peripheral resistance?

<p>Alpha 1 receptor (B)</p> Signup and view all the answers

Which of the following is a direct effect of catecholamines binding to beta 1 receptors?

<p>Increased lipolysis (B)</p> Signup and view all the answers

Catecholamines binding to which receptor is responsible for thermogenesis and lipolysis within adipose tissue?

<p>Beta 3 receptor (B)</p> Signup and view all the answers

Which effect of catecholamines is mediated through the stimulation of alpha 1 receptors?

<p>Mydriasis (eye dilation) (A)</p> Signup and view all the answers

Which of the following is a direct effect of catecholamines binding to beta 2 receptors?

<p>Increased muscle and liver glycogenolysis (D)</p> Signup and view all the answers

Which receptor is responsible for bronchodilation caused by catecholamines?

<p>Beta 2 receptor (B)</p> Signup and view all the answers

Which of the following effects of catecholamines is mediated through the stimulation of beta 1 receptors?

<p>Tachycardia (C)</p> Signup and view all the answers

Which effect of catecholamines is responsible for the increase in available glucose during acute stress?

<p>All of the above (D)</p> Signup and view all the answers

Which hormone is responsible for increasing libido and secondary sexual characteristics in humans?

<p>Androgens (D)</p> Signup and view all the answers

In the catecholamine synthesis pathway, what happens right after the conversion of L-DOPA to dopamine within the cytosol of the chromaffin cell?

<p>Dopamine is converted to norepinephrine, within a chromaffin granule (A)</p> Signup and view all the answers

What is the main function of norepinephrine (NE) in the catecholamine metabolism pathway?

<p>Exerts negative feedback on pre-ganglionic sympathetic receptors (A)</p> Signup and view all the answers

What is the first step in the metabolism of epinephrine (EPI) via the COMT pathway within catecholamine metabolism?

<p>EPI uses COMT to convert into metanephrine (C)</p> Signup and view all the answers

Which precursor molecule is converted into androstenedione in the androgen production pathway?

<p>Dehydroepiandrosterone (DHEA) (A)</p> Signup and view all the answers

What is the half-life of epinephrine (EPI) in the catecholamine metabolism pathway?

<p>2 minutes (A)</p> Signup and view all the answers

In the catecholamine synthesis pathway, what happens right after the conversion of dopamine into norepinephrine (NE)?

<p>Norepinephrine goes to the cytosol and is converted into epinephrine (D)</p> Signup and view all the answers

What is the primary function of catecholamines in the flight or fight response?

<p>Increase energy availability and overall metabolism (B)</p> Signup and view all the answers

Which of the following is NOT a function of cortisol in regulating gene expression?

<p>Photosynthesis regulation (B)</p> Signup and view all the answers

What is the primary role of cortisol in fat metabolism?

<p>Shifting metabolism from glucose to fat (B)</p> Signup and view all the answers

What is the primary source of amino acids for gluconeogenesis during cortisol-stimulated protein catabolism?

<p>Skeletal muscle (B)</p> Signup and view all the answers

What happens to free fatty acids (FFA) when cortisol levels are elevated?

<p>FFA are transported from adipose tissue to the liver and abdomen (C)</p> Signup and view all the answers

Which of the following is NOT a potential consequence of long-term excessive cortisol release?

<p>Increased protein synthesis (A)</p> Signup and view all the answers

What is the primary effect of cortisol on carbohydrate metabolism?

<p>Increasing blood glucose levels (B)</p> Signup and view all the answers

Which of the following is a factor that stimulates glucocorticoid production in the adrenal gland?

<p>All of the above (D)</p> Signup and view all the answers

What is the consequence of the surplus of free fatty acids (FFA) being redirected to the liver and abdomen?

<p>Increased visceral (abdominal) fat and a pot belly appearance (B)</p> Signup and view all the answers

Which statement accurately describes the effect of cortisol on glucose transport into fat cells?

<p>Cortisol inhibits glucose transport into fat cells (B)</p> Signup and view all the answers

What is the primary function of the hypothalamus in the HPA-axis?

<p>Produce CRH (A)</p> Signup and view all the answers

Which of the following statements about the diurnal rhythm of cortisol production is correct?

<p>Cortisol production is higher in the morning than at night. (A)</p> Signup and view all the answers

Which of the following is NOT a symptom associated with elevated cortisol levels, according to the text?

<p>Increased peripheral fat deposits (D)</p> Signup and view all the answers

High cortisol levels can lead to what illness that is also known as "Steroid Diabetes"?

<p>Diabetes Mellitus (D)</p> Signup and view all the answers

What is the primary source of energy for muscles when cortisol levels are elevated?

<p>Free fatty acids (FFA) (D)</p> Signup and view all the answers

What is the first step in the metabolism of norepinephrine (NE) via the MAO pathway within catecholamine metabolism?

<p>NE uses MAO to convert into dihydroxymandelic acid (D)</p> Signup and view all the answers

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