19 Questions
What are the first 3 phases of the cell cycle called?
G1, S, G2
Which cell type has a cell cycle of less than 20 minutes?
Embryo cells
Which type of cells divide frequently throughout life with a 12-24 hour cycle?
Skin cells
Which type of cells do not divide at all after maturity and remain permanently in G0 phase?
Mature nerve cells
What are cyclins and cyclin-dependent kinases known as in the regulation of the cell cycle?
Positive regulators
Which proteins act as negative regulators of the cell cycle and suppressors of cancer?
P53 and Rb
What is the main biochemical event occurring during the S phase of the cell cycle?
DNA synthesis
What is the importance of checkpoints in the cell cycle?
To stimulate DNA repair
Which type of genes are involved in suppressing cancer, especially by stimulating DNA repair, cell cycle, and apoptosis?
Tumor suppressor genes
What is the critical role of a multicellular organism in coordinating cell division?
Coordinating timing of cell division across different tissues & organs
During which phase does the cell replicate its nuclear DNA?
S phase
At which checkpoint does the cell determine if DNA synthesis has completed correctly?
G2/M checkpoint
What is the longest phase in the cell cycle?
G1 phase
Which phase marks the generation of bipolar mitotic spindles, segregation of sister chromatids, and cell division?
M phase
What happens during the G0 phase of the cell cycle?
Cell stays dormant until instructed to divide
Which phase involves RNA and protein synthesis but no DNA synthesis?
G1 phase
Which checkpoint checks if all chromosomes are attached to the spindle and if sister chromatids can separate correctly?
Spindle checkpoint
What is the purpose of checkpoint control systems in the cell cycle?
(External) (Internal) Regulation of DNA integrity
What occurs during the S Phase of the cell cycle?
The cell replicates its nuclear DNA.
Test your knowledge of the cell cycle and its regulation with this quiz from the Principles of Health and Disease block at Qassim University's College of Medicine. Explore the stages of the cell cycle, biochemical events during S phase, cyclins, cyclin-dependent kinases, checkpoints, and tumor suppressor genes.
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