Water Soluble Vitamins in Clinical Chemistry
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Questions and Answers

What is the primary function of Vitamin B1 in the body?

  • To activate iron and folic acid
  • To produce hormones by the adrenal glands
  • To maintain healthy skin, hair, and eyes
  • To help convert carbohydrates into energy (correct)
  • What are the two biologically active forms of Vitamin B2?

  • Pyridoxine and Biotin
  • FMN and FAD (correct)
  • FAD and Niacin
  • Riboflavin and Thiamine
  • Which of the following is NOT a function of Vitamin B2?

  • Converting tryptophan into niacin
  • Regulating blood pressure (correct)
  • Maintaining healthy eyes and nerves
  • Producing hormones by the adrenal glands
  • What is the common deficiency disease caused by a lack of Vitamin B1?

    <p>Beriberi</p> Signup and view all the answers

    Which of the following is NOT a water-soluble vitamin?

    <p>Vitamin D</p> Signup and view all the answers

    What is the role of Vitamin B1 in the nervous system?

    <p>To maintain healthy nerves</p> Signup and view all the answers

    What is the function of Flavin Adenine Dinucleotide (FAD) in the body?

    <p>As a coenzyme in oxidation/reduction reactions</p> Signup and view all the answers

    Which of the following vitamins is necessary for the absorption of iron?

    <p>Vitamin B2</p> Signup and view all the answers

    What is the term used for riboflavin deficiency?

    <p>Ariboflavinosis</p> Signup and view all the answers

    Which of the following is a symptom of vitamin B2 deficiency?

    <p>Cracks at the corners of the mouth</p> Signup and view all the answers

    Which vitamin is a precursor for the coenzymes NAD and NADP?

    <p>Vitamin B3</p> Signup and view all the answers

    What condition is caused by a deficiency of niacin?

    <p>Pellagra</p> Signup and view all the answers

    Which vitamin is involved in the formation of Coenzyme A?

    <p>Vitamin B5</p> Signup and view all the answers

    What is a common sign of riboflavin deficiency?

    <p>Mouth ulcers</p> Signup and view all the answers

    Which vitamin helps to convert nutrients into energy?

    <p>Vitamin B3</p> Signup and view all the answers

    What type of deficiency is very rare among the B vitamins?

    <p>Vitamin B5 deficiency</p> Signup and view all the answers

    Which of the following is NOT a symptom of severe vitamin B6 deficiency?

    <p>Vision loss</p> Signup and view all the answers

    What role does folic acid play during pregnancy?

    <p>It is essential for the biosynthesis of several compounds.</p> Signup and view all the answers

    What is one of the primary functions of vitamin B12?

    <p>Maintaining healthy nerve cells</p> Signup and view all the answers

    Which condition is associated with folic acid deficiency?

    <p>Megaloblastic anemia</p> Signup and view all the answers

    What is one of the major consequences of vitamin C deficiency?

    <p>Fragile blood capillaries</p> Signup and view all the answers

    Which vitamin serves as a precursor for the coenzyme pyridoxal phosphate?

    <p>Vitamin B6</p> Signup and view all the answers

    Which vitamin is known for its antioxidant properties?

    <p>Vitamin C</p> Signup and view all the answers

    Which vitamin deficiency can cause neurological problems?

    <p>Vitamin B12</p> Signup and view all the answers

    Study Notes

    Water Soluble Vitamins

    Vitamin B Complex

    • Composed of: Thiamine (B1), Riboflavin (B2), Niacin (B3), Pantothenic acid (B5), Pyridoxine (B6), Biotin (B7), Folic acid (B9), and Cobalamine (B12)
    • All Vitamin B complexes are coenzymes

    Energy Releasing Vitamins

    • Thiamine (B1)
    • Riboflavin (B2)
    • Niacin (B3)
    • Biotin (B7)
    • Pantothenic acid (B5)

    Hematobiotic Vitamins

    • Folic acid (B9)
    • Cobalamine (B12)

    Others

    • Pyridoxine (B6)

    Vitamin B1 (Thiamine)

    • Key role in carbohydrate metabolism
    • Acts as a coenzyme
    • Helps convert carbohydrates, fats, and protein into energy
    • Plays a role in the nervous system and good brain function
    • Deficiency leads to Beriberi, which can affect the cardiovascular system or central nervous system
    • Deficiency symptoms: mental problems, weak muscles, and cardiovascular symptoms

    Vitamin B2 (Riboflavin)

    • Plays a vital role in maintaining the body's energy supply
    • Helps break down proteins, fats, and carbohydrates
    • Contributes to the production of ATP
    • Biologically active forms: Flavin mononucleotide (FMN) and Flavin adenine dinucleotide (FAD)
    • Functions:
      • Converting tryptophan into niacin
      • Keeping eyes, nerves, muscles, skin, and liver healthy
      • Absorbing and activating iron, folic acid, and vitamins B1, B3, and B6
      • Hormone production by the adrenal glands
    • Deficiency: Ariboflavinosis, characterized by:
      • Angular cheilitis
      • Inflammation of the lining of the mouth and tongue
      • Mouth ulcers
      • Sore throat
      • Iron-deficiency anemia

    Vitamin B3 (Niacin)

    • Forms: Nicotinic acid and nicotinamide
    • Can be synthesized in the body from tryptophan
    • Functions:
      • Precursor for coenzymes NAD and NADP in oxidation-reduction reactions
      • Converts nutrients into energy, creates cholesterol and fats, and exerts antioxidant effects
    • Deficiency: Pellagra, characterized by:
      • Dark, scaly rash on skin exposed to sunlight
      • Bright redness of the tongue
      • Constipation/diarrhea

    Vitamin B5 (Pantothenic acid)

    • Part of Coenzyme A, essential for energy metabolism
    • Helps produce ATP from carbohydrate, protein, and fat breakdown
    • Functions:
      • Helps produce antibody
      • Helps in the production of cortisol
      • Formation of Acetylcholine and epinephrine
    • Deficiency: Rare, but can cause numbness and burning of hands and feet, headache, extreme tiredness, and gastrointestinal symptoms

    Vitamin B6

    • Acts as a precursor for coenzyme pyridoxal phosphate (PLP)
    • Important in amino acid and glycogen metabolism
    • Supports immune function and brain health
    • Used as an anti-emetic drug
    • Deficiency: Impaired immune function and neurological symptoms

    Vitamin B9 (Folic acid)

    • Essential for one-carbon metabolism and biosynthesis of several compounds
    • Need increases during pregnancy and cell multiplication
    • Function: Essential for the production of DNA and RNA
    • Deficiency: Megaloblastic anemia and neural tube defects

    Vitamin B12 (Cobalamin)

    • Important for maintaining healthy nerve cells
    • Helps in the production of DNA and RNA
    • Works closely with vitamin B9 to help make red blood cells and iron function
    • Deficiency: Pernicious anemia and neurological problems

    Vitamin C (Ascorbic acid)

    • Active form: Ascorbic acid
    • Humans cannot synthesize vitamin C and must obtain it from an external supply
    • Function:
      • Synthesis of collagen, the principal tissue protein
      • Acts as an antioxidant
    • Deficiency: Scurvy, characterized by skin changes, bleeding gums, tooth loss, fragile blood capillaries, and bone fracture

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    Description

    This quiz covers the classification and functions of water soluble vitamins, including Vitamin B complex and Vitamin C. It's a part of clinical chemistry lectures by Dr. Wael Sobhy Darwish.

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