Clinical Chemistry: Water Soluble Vitamins
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Questions and Answers

What is another name for Riboflavin deficiency?

  • Ariboflavinosis (correct)
  • Pellagra
  • Niacin deficiency
  • Pantothenic acid deficiency

What is the function of NAD and NADP in the body?

  • To help in the production of cortisol
  • In oxidation-reduction reactions (correct)
  • To produce antibody
  • To convert nutrients into energy

What is the primary function of Vitamin B5 or Pantothenic acid?

  • To help in the production of cortisol
  • To produce energy from carbohydrates, protein, and fat (correct)
  • To convert nutrients into energy
  • To produce antibody

What are the signs and symptoms of Vitamin B2 deficiency?

<p>All of the above (D)</p> Signup and view all the answers

What is the main cause of Riboflavin deficiency?

<p>Both A and B (B)</p> Signup and view all the answers

What is the function of Niacin in the body?

<p>All of the above (D)</p> Signup and view all the answers

What is the condition caused by a Vitamin B3 deficiency?

<p>Pellagra (D)</p> Signup and view all the answers

Which of the following vitamins is synthesized in the body from the essential amino acid Tryptophan?

<p>Vitamin B3 (A)</p> Signup and view all the answers

What is the primary function of Vitamin B1 (Thiamine) in the body?

<p>Conversion of carbohydrates, fats, and proteins into energy (C)</p> Signup and view all the answers

Which of the following vitamins is NOT directly involved in energy releasing processes?

<p>Vitamin B9 (B)</p> Signup and view all the answers

What is the name of the condition that results from a deficiency of Vitamin B1?

<p>Beriberi (A)</p> Signup and view all the answers

Which of the following is NOT a function of Vitamin B2 (Riboflavin)?

<p>Production of red blood cells (D)</p> Signup and view all the answers

Which of the following vitamins is a coenzyme in oxidation/reduction reactions?

<p>All of the above (D)</p> Signup and view all the answers

Which two Vitamin B complex members are directly involved in hematobiotic processes, meaning they are essential for the production of red blood cells?

<p>Vitamin B9 and Vitamin B12 (B)</p> Signup and view all the answers

Which of the following is NOT a symptom of Vitamin B1 deficiency?

<p>Scurvy (A)</p> Signup and view all the answers

What is the main function of the two biologically active forms of Vitamin B2, FMN and FAD?

<p>They act as coenzymes in oxidation/reduction reactions (B)</p> Signup and view all the answers

What is a common consequence of severe vitamin B6 deficiency?

<p>Decreased appetite (A), Nausea and vomiting (C)</p> Signup and view all the answers

Which of the following functions is primarily associated with vitamin B12?

<p>Maintenance of healthy nerve cells (B)</p> Signup and view all the answers

A deficiency in folic acid can lead to which of the following conditions?

<p>Megaloblastic anemia (B)</p> Signup and view all the answers

Which vitamin is noted for its role in the synthesis of collagen?

<p>Vitamin C (B)</p> Signup and view all the answers

What condition is associated with vitamin B12 deficiency?

<p>Pernicious anemia (A)</p> Signup and view all the answers

What is the primary function of folic acid during pregnancy?

<p>Supporting nerve cell growth (C)</p> Signup and view all the answers

Which symptom might indicate a vitamin C deficiency?

<p>Fragile blood capillaries (C)</p> Signup and view all the answers

What is a key role of pyridoxal phosphate (PLP) in the body?

<p>Amino acid metabolism (C)</p> Signup and view all the answers

Flashcards

What is Vitamin B Complex?

Vitamin B complex is a group of eight water-soluble vitamins essential for various metabolic processes. They act as coenzymes, assisting in the facilitation of enzymatic reactions.

What are the individual vitamins in Vitamin B complex?

Thiamine (B1), Riboflavin (B2), Niacin (B3), Pantothenic acid (B5), Pyridoxine (B6), Biotin (B7), Folic acid (B9), and Cobalamine (B12) are the eight vitamins that constitute Vitamin B complex.

Which vitamins in B complex are involved in energy production?

Thiamine (B1), Riboflavin (B2), Niacin (B3), Biotin (B7), and Pantothenic acid (B5) are essential for energy production in the body. They play a crucial role in converting nutrients into usable energy.

Which B vitamins are important for blood formation and DNA synthesis?

Folic acid (B9) and Cobalamine (B12) are essential for the production of red blood cells and the formation of DNA and RNA.

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What is the role of vitamin B6 in the body?

Pyridoxine (B6) plays a role in amino acid metabolism and is essential for immune function and brain health. It also helps in the synthesis of neurotransmitters.

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What is the role of Thiamine (B1) in the body?

Thiamine (B1) plays a crucial role in carbohydrate metabolism, acting as a coenzyme. It helps convert carbohydrates into energy and is essential for nerve function.

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What is Beriberi and what causes it?

Beriberi is a disease caused by thiamine (B1) deficiency. It affects the cardiovascular system and central nervous system, manifesting as weakness, mental problems, and heart issues.

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What is the role of Riboflavin (B2) in the body?

Riboflavin (B2) is crucial for energy production, converting food into ATP. It is also involved in maintaining healthy skin, eyes, and nerves.

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What is Ariboflavinosis and what are its symptoms?

Ariboflavinosis is a deficiency of Riboflavin (B2) characterized by inflammation of the mouth and tongue, cheilitis, and anemia.

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What is the role of Niacin (B3) in the body?

Niacin (B3) is involved in energy production, cholesterol synthesis, and antioxidant effects. It is also a precursor for coenzymes essential for various metabolic reactions.

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What is Pellagra and what are its symptoms?

Pellagra is a deficiency of Niacin (B3) characterized by skin rashes, diarrhea, and cognitive impairment.

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What is the role of Pantothenic acid (B5) in the body?

Pantothenic acid (B5) is a component of Coenzyme A, essential for energy metabolism. It is also involved in the production of hormones and antibodies.

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What are the symptoms of Pantothenic acid (B5) deficiency?

Pantothenic acid (B5) deficiency is rare but can lead to fatigue, numbness, and digestive issues.

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What is the role of Pyridoxine (B6) in the body?

Pyridoxine (B6) is a precursor for pyridoxal phosphate (PLP), a coenzyme involved in amino acid metabolism. It also supports immune function and brain health.

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What is the role of Folic acid (B9) in the body?

Folic acid (B9) is crucial for DNA and RNA synthesis and is essential for cell division and growth. It is particularly important during pregnancy.

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What are the conditions caused by folic acid (B9) deficiency?

Megaloblastic anemia and neural tube defects are conditions caused by folic acid (B9) deficiency.

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What is the role of Cobalamin (B12) in the body?

Cobalamin (B12) is essential for the formation of red blood cells and the maintenance of healthy nerves. It also helps in the synthesis of DNA.

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What are the conditions caused by Cobalamin (B12) deficiency?

Pernicious anemia and neurological problems are conditions associated with Cobalamin (B12) deficiency.

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What is Vitamin C?

Vitamin C, also known as ascorbic acid, is an essential water-soluble vitamin that humans cannot produce. It is crucial for collagen synthesis and acts as an antioxidant.

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What is the role of vitamin C in collagen synthesis?

Collagen is a structural protein found in skin, bones, cartilage, and tendons. Vitamin C plays a crucial role in forming collagen, providing structural support to these tissues.

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What is Scurvy and what are its symptoms?

Scurvy is a deficiency disease caused by a lack of vitamin C. It is characterized by bleeding gums, weakened blood vessels, and poor wound healing.

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Study Notes

Water Soluble Vitamins

Vitamin B Complex

  • Composed of: Thiamine (B1), Riboflavin (B2), Niacin (B3), Pantothenic acid (B5), Pyridoxine (B6), Biotin (B7), Folic acid (B9), and Cobalamine (B12)
  • All Vitamin B complexes are coenzymes

Energy Releasing Vitamins

  • Thiamine (B1)
  • Riboflavin (B2)
  • Niacin (B3)
  • Biotin (B7)
  • Pantothenic acid (B5)

Hematobiotic Vitamins

  • Folic acid (B9)
  • Cobalamine (B12)

Others

  • Pyridoxine (B6)

Vitamin B1 (Thiamine)

  • Key role in carbohydrate metabolism
  • Acts as a coenzyme
  • Helps convert carbohydrates, fats, and protein into energy
  • Plays a role in the nervous system and good brain function
  • Deficiency leads to Beriberi, which can affect the cardiovascular system or central nervous system
  • Deficiency symptoms: mental problems, weak muscles, and cardiovascular symptoms

Vitamin B2 (Riboflavin)

  • Plays a vital role in maintaining the body's energy supply
  • Helps break down proteins, fats, and carbohydrates
  • Contributes to the production of ATP
  • Biologically active forms: Flavin mononucleotide (FMN) and Flavin adenine dinucleotide (FAD)
  • Functions:
    • Converting tryptophan into niacin
    • Keeping eyes, nerves, muscles, skin, and liver healthy
    • Absorbing and activating iron, folic acid, and vitamins B1, B3, and B6
    • Hormone production by the adrenal glands
  • Deficiency: Ariboflavinosis, characterized by:
    • Angular cheilitis
    • Inflammation of the lining of the mouth and tongue
    • Mouth ulcers
    • Sore throat
    • Iron-deficiency anemia

Vitamin B3 (Niacin)

  • Forms: Nicotinic acid and nicotinamide
  • Can be synthesized in the body from tryptophan
  • Functions:
    • Precursor for coenzymes NAD and NADP in oxidation-reduction reactions
    • Converts nutrients into energy, creates cholesterol and fats, and exerts antioxidant effects
  • Deficiency: Pellagra, characterized by:
    • Dark, scaly rash on skin exposed to sunlight
    • Bright redness of the tongue
    • Constipation/diarrhea

Vitamin B5 (Pantothenic acid)

  • Part of Coenzyme A, essential for energy metabolism
  • Helps produce ATP from carbohydrate, protein, and fat breakdown
  • Functions:
    • Helps produce antibody
    • Helps in the production of cortisol
    • Formation of Acetylcholine and epinephrine
  • Deficiency: Rare, but can cause numbness and burning of hands and feet, headache, extreme tiredness, and gastrointestinal symptoms

Vitamin B6

  • Acts as a precursor for coenzyme pyridoxal phosphate (PLP)
  • Important in amino acid and glycogen metabolism
  • Supports immune function and brain health
  • Used as an anti-emetic drug
  • Deficiency: Impaired immune function and neurological symptoms

Vitamin B9 (Folic acid)

  • Essential for one-carbon metabolism and biosynthesis of several compounds
  • Need increases during pregnancy and cell multiplication
  • Function: Essential for the production of DNA and RNA
  • Deficiency: Megaloblastic anemia and neural tube defects

Vitamin B12 (Cobalamin)

  • Important for maintaining healthy nerve cells
  • Helps in the production of DNA and RNA
  • Works closely with vitamin B9 to help make red blood cells and iron function
  • Deficiency: Pernicious anemia and neurological problems

Vitamin C (Ascorbic acid)

  • Active form: Ascorbic acid
  • Humans cannot synthesize vitamin C and must obtain it from an external supply
  • Function:
    • Synthesis of collagen, the principal tissue protein
    • Acts as an antioxidant
  • Deficiency: Scurvy, characterized by skin changes, bleeding gums, tooth loss, fragile blood capillaries, and bone fracture

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Description

This quiz covers water soluble vitamins, including Vitamin B complex and Vitamin C. Topics include energy releasing and hematobiotic functions of different vitamins.

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