Water Absorption in Distal Tubule

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What is the primary function of aldosterone in the renin-angiotensin-aldosterone pathway?

Promoting sodium and water reabsorption

What is the effect of caffeine on sodium reabsorption in the nephron?

Decreases sodium reabsorption

What is the primary mechanism of water reabsorption in the collecting duct?

osmotic gradient

What is the role of aquaporin 2 in the collecting duct?

Facilitates water reabsorption

What is the effect of ADH on water reabsorption in the collecting duct?

Increases water reabsorption

What is the primary stimulus for ADH release?

Increased blood osmolarity

What is the effect of aldosterone on the apical membrane of the collecting duct?

Increases the number of open Na+ and K+ channels

What is the role of the renin-angiotensin-aldosterone pathway in regulating blood pressure?

Increases blood pressure

What is the effect of sodium reabsorption on water reabsorption in the nephron?

Sodium reabsorption increases water reabsorption

What is the primary mechanism of renal water conservation?

Increased sodium reabsorption

What is the primary function of aquaporin 2 in the apical membrane of the collecting duct?

To allow for water reabsorption dependent on ADH

Which of the following is a characteristic of the epithelium in the distal tubule and collecting duct?

Permeable to water and does not contain Na+/K+/Cl- contransporters

What is the primary effect of ADH on the kidneys?

To increase the amount of water reabsorbed

What is the maximum osmolarity of urine that can be achieved in the kidney?

1400 mOsm

What is the primary stimulus for the release of ADH?

An increase in osmolarity of the extracellular fluid

What is the effect of ADH on the epithelium of the collecting duct?

It increases the permeability of the epithelium to water

What is the role of the countercurrent multiplier in the kidney?

To establish the osmotic gradient that allows for water reabsorption

What is the effect of a decrease in mean arterial pressure on ADH secretion?

It increases ADH secretion

What percentage of water is reabsorbed in the proximal tubule?

70%

What is the primary function of aquaporin 3 in the basolateral membrane?

To facilitate the transport of water back into the bloodstream

What is the primary function of aquaporins in the descending loop of Henle?

To make the epithelium permeable to water in response to the osmotic gradient

What is the result of the osmotic gradient in the descending loop of Henle?

Water moves out of the lumen, decreasing the osmolarity

What is the role of urea in the nephron?

To support the necessary osmotic gradient that allows for water movement to occur

What is the name of the capillaries surrounding the loop of Henle and nephrons?

Vasa recta

What is the direction of water movement in the ascending limb of the vasa recta?

Water moves into the capillaries from the interstitial fluid

What is the result of the lack of urea transporters in the ascending limb of the vasa recta?

The osmolarity of the ascending limb increases

What is the primary function of the loop of Henle?

To maintain the osmotic gradient necessary for water reabsorption

What is the role of ADH in the kidney?

To increase the permeability of the epithelium to water

What is the result of the osmotic gradient in the ascending loop of Henle?

Sodium ions move out of the lumen, decreasing the osmolarity

What is the primary function of the vasa recta in the kidney?

To allow for the exchange of solutes and water between the loop of Henle and the blood

Test your knowledge on the characteristics of the distal tubule in the nephron, including water permeability and ion transport. Identify the correct statement about the distal tubule in the kidney. Review your understanding of water absorption in the distal tubule.

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