Podcast
Questions and Answers
What is the function of Vitamin E?
What is the function of Vitamin E?
Vitamin K is essential for normal spermatogenesis.
Vitamin K is essential for normal spermatogenesis.
False
What is the effect of Vitamin E deficiency on the body?
What is the effect of Vitamin E deficiency on the body?
Atherosclerosis and heart diseases, oxidative stress leading to muscle weakness and arrhythmia, and vision problems.
Vitamin K is necessary for the synthesis of ____________________ in the liver.
Vitamin K is necessary for the synthesis of ____________________ in the liver.
Signup and view all the answers
What is the function of Folic Acid (FH4) in one-carbon metabolism?
What is the function of Folic Acid (FH4) in one-carbon metabolism?
Signup and view all the answers
Match the vitamins with their functions:
Match the vitamins with their functions:
Signup and view all the answers
What is a cause of Vitamin K deficiency?
What is a cause of Vitamin K deficiency?
Signup and view all the answers
Folic acid supplementation increases the risk of neural tube defects.
Folic acid supplementation increases the risk of neural tube defects.
Signup and view all the answers
What is the role of Folic Acid in the synthesis of DNA?
What is the role of Folic Acid in the synthesis of DNA?
Signup and view all the answers
Vitamin E is essential for normal spermatogenesis.
Vitamin E is essential for normal spermatogenesis.
Signup and view all the answers
What is the effect of Vitamin K on blood clotting?
What is the effect of Vitamin K on blood clotting?
Signup and view all the answers
Methotrexate competitively inhibits ______________________ enzyme.
Methotrexate competitively inhibits ______________________ enzyme.
Signup and view all the answers
What is the cause of megaloblastic anemia in Folic Acid deficiency?
What is the cause of megaloblastic anemia in Folic Acid deficiency?
Signup and view all the answers
Sulfonamides are folic acid agonists.
Sulfonamides are folic acid agonists.
Signup and view all the answers
Match the following folic acid antagonists with their uses:
Match the following folic acid antagonists with their uses:
Signup and view all the answers
What is the biochemical indicator of folate deficiency?
What is the biochemical indicator of folate deficiency?
Signup and view all the answers
Study Notes
Vitamin E
- Acts as a natural antioxidant due to the presence of the tocol ring, breaking free radicals.
- Maintains the integrity of the endothelium of blood vessels and stability of erythrocytes.
- Essential for normal spermatogenesis and continuation of pregnancy in rats.
- Increases the synthesis of Heme.
- Prevents the oxidation of vitamin A and β carotene.
- Protects against heart diseases by preventing the oxidation of LDL.
Vitamin E Deficiency
- Can lead to atherosclerosis and heart diseases.
- Causes oxidative stress, resulting in muscle weakness, arrhythmia, and vision problems.
Vitamin K
- Biochemical role depends on the synthesis of γ-carboxyglutamate.
- Essential for the hepatic synthesis of prothrombin and blood clotting factors VII, IX, and X.
- Interacts with platelets to form a prothrombin-calcium complex, which binds to phospholipids for blood clotting.
- Activates osteocalcin, converting pro-osteocalcin to osteocalcin.
Vitamin K Deficiency
- Uncommon due to adequate production by intestinal bacteria or obtained from the diet.
- Leads to internal and external hemorrhages.
- Caused by malabsorption syndrome, liver diseases, sterile intestine in newborns, prolonged use of antibiotics, and warfarin or dicumarol.
Folic Acid (Folate)
- Acts as a one-carbon metabolism, receiving one-carbon fragments and transferring them to amino acids, purines, and thymidine monophosphate (TMP) in DNA synthesis.
- Essential for DNA synthesis, synthesizing thymidine monophosphate (TMP).
- Necessary for the synthesis of red blood cells.
- Converts homocysteine to methionine, treating heart diseases.
- Prevents neural tube defects, such as Spina bifida and anencephaly.
Folic Acid Antagonists
- Methotrexate competitively inhibits folic acid reductase enzyme, blocking synthesis of nucleic acids and inhibiting cell division.
- Sulfonamides competitively inhibit folic acid reductase enzyme, preventing the formation of active forms of folic acid.
Folic Acid Deficiency
- Caused by increased demand, poor absorption, chronic alcoholism, diet lacking folic acid, drugs, and rapid growing cancer.
- Symptoms include megaloblastic anemia, leucopenia, thrombocytopenia, impaired growth, and neural tube defects.
- FIGLU test is a biochemical indicator of folate deficiency, accumulating in urine.
Studying That Suits You
Use AI to generate personalized quizzes and flashcards to suit your learning preferences.
Description
Learn about the essential functions of Vitamin E, including its role as a natural antioxidant, its effects on blood vessels and erythrocytes, and its importance in pregnancy and heart disease prevention.
