Virology Lab 7: Viruses Definition and Importance
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Questions and Answers

What is the main principle of fluorescence microscopy in detecting viral antigens?

  • Measuring the size of viral particles
  • Detecting the morphology of virions
  • Detecting fluorescent dye linked to antibody molecules (correct)
  • Observing the inclusion bodies in the nucleus
  • What is the term for the structural changes in a host cell resulting from viral infection?

  • Inclusion bodies formation
  • Viral growth
  • Cell transformation
  • Cytopathogenic effect (correct)
  • Which of the following is an example of cytopathogenic effect?

  • Giant cell formation in measles
  • Inclusion bodies in the nucleus
  • Cluster formation in adenovirus (correct)
  • Cell transformation
  • What is the term for the formation of a giant cell with many nuclei?

    <p>Syncytium formation</p> Signup and view all the answers

    What is the term for the change in growth characteristics of infected cells?

    <p>Cell transformation</p> Signup and view all the answers

    What are inclusion bodies?

    <p>Nuclear or cytoplasmic aggregates of virus particles</p> Signup and view all the answers

    What is the composition of Negri bodies in rabies infected brain cells?

    <p>Rabies virus proteins and RNA</p> Signup and view all the answers

    What is the appearance of Gaurnieri bodies in Poxvirus-infected epithelial cells?

    <p>Pink blobs in the cytoplasm</p> Signup and view all the answers

    What is the characteristic appearance of intranuclear inclusions in cytomegalovirus infection?

    <p>Owl's eye intranuclear bodies</p> Signup and view all the answers

    What is the location of Negri bodies in rabies infected brain cells?

    <p>Cytoplasm of infected neurons</p> Signup and view all the answers

    What is the virus associated with Nuclear bodies?

    <p>Adenovirus</p> Signup and view all the answers

    What is the characteristic of viruses that defines them as obligate intracellular parasites?

    <p>They depend on the host for their survival.</p> Signup and view all the answers

    What is the principle of phage typing of bacteria?

    <p>Bacterial strains are grown on a suitable culture medium and then subjected to attack by a series of different known phages.</p> Signup and view all the answers

    What is the purpose of Viral Transport Medium (VTM)?

    <p>To preserve viral infectivity within the specimen and prevent it from drying.</p> Signup and view all the answers

    What is the name of the continuous cell line used in tissue culture for virus cultivation?

    <p>Hela cell</p> Signup and view all the answers

    What is the method used to determine the number of viral particles in a sample?

    <p>Plaque assay</p> Signup and view all the answers

    What is the name of the solution that must be present in Viral Transport Medium (VTM)?

    <p>Hank's solution</p> Signup and view all the answers

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