Podcast
Questions and Answers
Which process is responsible for virus budding by cellular exocytosis?
Which process is responsible for virus budding by cellular exocytosis?
What is responsible for directing assembly and budding of HIV at the cell membrane?
What is responsible for directing assembly and budding of HIV at the cell membrane?
Which type of viral egress involves the formation of double-membrane vesicles?
Which type of viral egress involves the formation of double-membrane vesicles?
What can antivirals target in order to inhibit many steps of viral transmission?
What can antivirals target in order to inhibit many steps of viral transmission?
Signup and view all the answers
During which phase of the viral life cycle does the attachment to host cells occur?
During which phase of the viral life cycle does the attachment to host cells occur?
Signup and view all the answers
What step occurs during the penetration phase of the viral life cycle?
What step occurs during the penetration phase of the viral life cycle?
Signup and view all the answers
When does the manufacture of viral components take place in the viral life cycle?
When does the manufacture of viral components take place in the viral life cycle?
Signup and view all the answers
What is formed during the assembly step in the viral life cycle?
What is formed during the assembly step in the viral life cycle?
Signup and view all the answers
In which phase of the viral life cycle do new virus particles (virions) increase before release occurs?
In which phase of the viral life cycle do new virus particles (virions) increase before release occurs?
Signup and view all the answers
In which organelle does replication of the genetic material occur for dsDNA viruses like Herpes simplex viruses?
In which organelle does replication of the genetic material occur for dsDNA viruses like Herpes simplex viruses?
Signup and view all the answers
Which type of virus replication is characterized by a cytoplasmic-only process with no DNA form?
Which type of virus replication is characterized by a cytoplasmic-only process with no DNA form?
Signup and view all the answers
What is the enzyme responsible for replicating the genetic material in Retroviruses?
What is the enzyme responsible for replicating the genetic material in Retroviruses?
Signup and view all the answers
Which type of virus replication can occur either in the cytoplasm or within the nucleus?
Which type of virus replication can occur either in the cytoplasm or within the nucleus?
Signup and view all the answers
Where does viral assembly typically happen in an infected cell?
Where does viral assembly typically happen in an infected cell?
Signup and view all the answers
What is the primary mode of virus release and transmission for enveloped viruses?
What is the primary mode of virus release and transmission for enveloped viruses?
Signup and view all the answers
Which viral infection was associated with microcephaly in infants during the Brazil epidemic of 2016?
Which viral infection was associated with microcephaly in infants during the Brazil epidemic of 2016?
Signup and view all the answers
What type of receptor initiates the penetration of viral particles into cells during virus entry?
What type of receptor initiates the penetration of viral particles into cells during virus entry?
Signup and view all the answers
Why are RNA viruses considered an exception to the Central Dogma of Molecular Biology?
Why are RNA viruses considered an exception to the Central Dogma of Molecular Biology?
Signup and view all the answers
What is responsible for the replication of genetic material in dsDNA gapped viruses?
What is responsible for the replication of genetic material in dsDNA gapped viruses?
Signup and view all the answers
Which organelle plays a role in viral assembly and maturation for enveloped viruses?
Which organelle plays a role in viral assembly and maturation for enveloped viruses?
Signup and view all the answers
Viral proteins responsible for directing assembly and budding are not involved in membrane curvature.
Viral proteins responsible for directing assembly and budding are not involved in membrane curvature.
Signup and view all the answers
Exosomes are not associated with non-lytic viral egress.
Exosomes are not associated with non-lytic viral egress.
Signup and view all the answers
Antivirals can target only one step in the viral transmission process.
Antivirals can target only one step in the viral transmission process.
Signup and view all the answers
HIV Budding Assembly is unrelated to the formation of lentivirus nucleocapsid linked to the budding process.
HIV Budding Assembly is unrelated to the formation of lentivirus nucleocapsid linked to the budding process.
Signup and view all the answers
During the maturation phase of the viral life cycle, new virus particles (virions) are formed before release occurs.
During the maturation phase of the viral life cycle, new virus particles (virions) are formed before release occurs.
Signup and view all the answers
Viruses can 'grow' in the same way as cells do.
Viruses can 'grow' in the same way as cells do.
Signup and view all the answers
The attachment phase of the viral life cycle involves the manufacture of viral components such as viral proteins and new genetic materials.
The attachment phase of the viral life cycle involves the manufacture of viral components such as viral proteins and new genetic materials.
Signup and view all the answers
Viruses rely on their host cell to provide the necessary tools for their replication and assembly.
Viruses rely on their host cell to provide the necessary tools for their replication and assembly.
Signup and view all the answers
Viral egress by the formation of double-membrane vesicles is a characteristic of all types of viruses.
Viral egress by the formation of double-membrane vesicles is a characteristic of all types of viruses.
Signup and view all the answers
The penetration phase of the viral life cycle occurs after the manufacture of viral proteins and genetic materials.
The penetration phase of the viral life cycle occurs after the manufacture of viral proteins and genetic materials.
Signup and view all the answers
All viruses on the planet follow the rule of making mRNA that can be read by host ribosomes, with no known exception?
All viruses on the planet follow the rule of making mRNA that can be read by host ribosomes, with no known exception?
Signup and view all the answers
The cytoplasm is an easy environment for viruses to penetrate due to its spacious nature?
The cytoplasm is an easy environment for viruses to penetrate due to its spacious nature?
Signup and view all the answers
Retroviruses can bind to 16 different receptors?
Retroviruses can bind to 16 different receptors?
Signup and view all the answers
Flaviviruses like Zika virus replicate their genetic material in the cell nucleus?
Flaviviruses like Zika virus replicate their genetic material in the cell nucleus?
Signup and view all the answers
Herpes simplex viruses utilize DNA dependent RNA polymerase encoded by host cells for replication of their genetic material?
Herpes simplex viruses utilize DNA dependent RNA polymerase encoded by host cells for replication of their genetic material?
Signup and view all the answers
Virus budding by cellular exocytosis involves the formation of double-membrane vesicles?
Virus budding by cellular exocytosis involves the formation of double-membrane vesicles?
Signup and view all the answers
All (+) RNA is mRNA?
All (+) RNA is mRNA?
Signup and view all the answers
Influenza virus, a ss (-) RNA virus, can replicate its genetic material in both cytoplasmic and nuclear environments?
Influenza virus, a ss (-) RNA virus, can replicate its genetic material in both cytoplasmic and nuclear environments?
Signup and view all the answers
Virus assembly and budding typically occur in the cell membrane?
Virus assembly and budding typically occur in the cell membrane?
Signup and view all the answers
RNA viruses are considered an exception to the Central Dogma of Molecular Biology because their molecular biology does not involve DNA?
RNA viruses are considered an exception to the Central Dogma of Molecular Biology because their molecular biology does not involve DNA?
Signup and view all the answers
Viral genomes can fall into any of the seven classes of viral genomes based on their structure?
Viral genomes can fall into any of the seven classes of viral genomes based on their structure?
Signup and view all the answers
Viral release by cellular exocytosis often involves the use of the secretory pathway for assembly, maturation, and egress from the cell?
Viral release by cellular exocytosis often involves the use of the secretory pathway for assembly, maturation, and egress from the cell?
Signup and view all the answers
Study Notes
- Dr. Marine Petit discusses virus life cycle in the context of cellular microbiology and virology.
- A virus is not capable of independent growth and replication; it depends on the host cell for these functions.
- Virus life cycle consists of attachment and entry, protein translation, genome replication, and virus assembly and release.
- Virus attachment and entry is facilitated by recognition of attachment and entry receptors by glycoproteins on the surface of the virus.
- Uncoating occurs in the cytoplasm or within the nucleus, and can be facilitated by the hijacking of the microtubule network.
- Virus protein translation is carried out using the host cell's translation machinery.
- Virus genomes are diverse and include DNA and RNA forms, each with unique replication strategies.
- dsDNA viruses have DNA-dependent DNA and RNA polymerases encoded by the host cells for genome replication.
- RNA viruses have RNA-dependent RNA polymerases encoded by the virus for replication.
- Virus assembly occurs in the infected cell, with viral factories being created using the membrane.
- Virus release and transmission can occur through cellular exocytosis, lytic or non-lytic methods, and cell-to-cell contact.
- Antivirals can target various stages of the virus life cycle for inhibition.
- Understanding viruses requires knowledge of cell biology and molecular biology, and virology is an integrative science.
Studying That Suits You
Use AI to generate personalized quizzes and flashcards to suit your learning preferences.
Related Documents
Description
This lecture overview covers the introduction to virus life cycle, including virus entry and uncoating, virus protein translation, genome replication, virus assembly, virus release and transmission. It emphasizes the dependency of viruses on host cells and the need for understanding cell biology and molecular biology to comprehend viruses.
