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Questions and Answers
What is the trade name of Venlafaxine?
What is the trade name of Venlafaxine?
What classification does Venlafaxine fall under?
What classification does Venlafaxine fall under?
Antidepressant, anxiolytic
What is the FDA category for Venlafaxine?
What is the FDA category for Venlafaxine?
C
What is the pharmacological detail about Venlafaxine?
What is the pharmacological detail about Venlafaxine?
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What is Venlafaxine's mechanism of action?
What is Venlafaxine's mechanism of action?
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Dosage for immediate release (IR) is _____ mg.
Dosage for immediate release (IR) is _____ mg.
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Dosage for extended release (ER) is _____ mg.
Dosage for extended release (ER) is _____ mg.
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Dosage for ER capsules is _____ mg.
Dosage for ER capsules is _____ mg.
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What is the recommended dose for treatment of depression?
What is the recommended dose for treatment of depression?
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Which of the following are side effects of Venlafaxine? (Select all that apply)
Which of the following are side effects of Venlafaxine? (Select all that apply)
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Venlafaxine should be used in pregnancy.
Venlafaxine should be used in pregnancy.
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What should be monitored in patients taking Venlafaxine?
What should be monitored in patients taking Venlafaxine?
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What should patients avoid when taking Venlafaxine?
What should patients avoid when taking Venlafaxine?
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Study Notes
Venlafaxine Overview
- Generic name: Venlafaxine; Trade name: Effexor XR
- Classification: Antidepressant, anxiolytic
- FDA Pregnancy Category: C
Pharmacology
- Metabolism: Mainly converted to desvenlafaxine in the liver, which is an active metabolite.
- Absorption: Well absorbed orally, with or without food.
- Half-life: 5 hours for venlafaxine, 11 hours for desvenlafaxine.
Mechanism of Action
- First available serotonin-norepinephrine reuptake inhibitor (SNRI).
- Approved for major depression, generalized anxiety disorder, social anxiety disorder, and panic disorder.
- Strongly inhibits norepinephrine (NE) and serotonin (5-HT) reuptake, weakly inhibits dopamine reuptake.
Dosage Information
- Immediate release (IR): 25 - 100 mg.
- Extended release (ER): 37.5 - 225 mg.
- ER capsule (Effexor XR): 37.5 - 150 mg.
- Treatment for depression: Starting dose of 75 mg; max typically 225 mg.
Side Effects
- Common: Nausea, headache, anorexia, nervousness, sweating, somnolence, weight loss, dizziness, dry mouth.
- Serious: Hypertension, angle closure glaucoma, sexual dysfunction, hyponatremia, suicidal thoughts or actions.
Contraindications/Interactions
- Not recommended during pregnancy.
- Avoid combining with MAOIs, serotonergic drugs, St. John's Wort, trazodone, or alcohol.
Nursing Considerations
- Monitor for signs of suicidal thoughts or actions, particularly in children and young adults.
- MAOIs must be stopped at least 14 days before starting venlafaxine and should be discontinued 7 days prior to switching to an MAOI.
- Consider dosage reduction in patients with liver or potentially kidney disease.
Patient Education
- Advise against use during pregnancy.
- Instruct patients to swallow ER capsules whole; do not cut, crush, or chew.
- Take medication with food, avoid alcohol and St. John's Wort.
- Report any rash or suicidal thoughts and do not discontinue abruptly.
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Description
This quiz offers flashcards covering important definitions and classifications related to Venlafaxine, an antidepressant medication. Learn about its generic name, FDA category, and pharmacologic details to enhance your understanding of this drug.
