Podcast
Questions and Answers
What triggers muscle contraction by binding to actin to form a cross-bridge?
What triggers muscle contraction by binding to actin to form a cross-bridge?
- Myosin (correct)
- Actin
- MLC phosphatase
- Ca2+
What is the approximate percentage of total cardiac output supplied by the left and right coronary arteries?
What is the approximate percentage of total cardiac output supplied by the left and right coronary arteries?
- 15%
- 5% (correct)
- 20%
- 11%
How is the balance between oxygen supply and demand in a normal heart affected during exercise?
How is the balance between oxygen supply and demand in a normal heart affected during exercise?
- O2 supply increases, O2 demand decreases
- O2 supply and demand both decrease
- O2 supply and demand both increase (correct)
- O2 supply decreases, O2 demand increases
Which condition results from a complete block in a coronary artery?
Which condition results from a complete block in a coronary artery?
What characterizes Unstable Angina compared to Stable Angina?
What characterizes Unstable Angina compared to Stable Angina?
In Ischemic Heart Disease, what leads to the occurrence of Angina Pectoris?
In Ischemic Heart Disease, what leads to the occurrence of Angina Pectoris?
What is the duration of action of nitroglycerin?
What is the duration of action of nitroglycerin?
Which formulation of nitroglycerin is most suitable for long-term prophylaxis of anginal attacks?
Which formulation of nitroglycerin is most suitable for long-term prophylaxis of anginal attacks?
How does the translingual spray formulation of nitroglycerin bypass liver inactivation?
How does the translingual spray formulation of nitroglycerin bypass liver inactivation?
Which condition is effectively treated with intravenous (IV) nitroglycerin?
Which condition is effectively treated with intravenous (IV) nitroglycerin?
Why is the sublingual formulation of nitroglycerin preferred for terminating an ongoing anginal attack?
Why is the sublingual formulation of nitroglycerin preferred for terminating an ongoing anginal attack?
What is the goal of therapies for variant angina (Prinzmetal's angina)?
What is the goal of therapies for variant angina (Prinzmetal's angina)?
Which drug class can lead to vasospasm in patients with variant angina?
Which drug class can lead to vasospasm in patients with variant angina?
What is the mechanism of action of organic nitrites & nitrates in treating angina?
What is the mechanism of action of organic nitrites & nitrates in treating angina?
Why should organic nitrites & nitrates not be used together with Sildenafil (PDE5 inhibitor)?
Why should organic nitrites & nitrates not be used together with Sildenafil (PDE5 inhibitor)?
Which of the following is a side effect associated with Amyl Nitrite inhalation?
Which of the following is a side effect associated with Amyl Nitrite inhalation?
What is the main mechanism of antianginal action for organic nitrites and nitrates?
What is the main mechanism of antianginal action for organic nitrites and nitrates?
Which adverse effect is commonly associated with excessive vasodilation from nitrites and nitrates?
Which adverse effect is commonly associated with excessive vasodilation from nitrites and nitrates?
How is tolerance to nitrates typically prevented?
How is tolerance to nitrates typically prevented?
Which enzyme involved in the mechanism of antianginal action is inactivated by oxygen free radicals?
Which enzyme involved in the mechanism of antianginal action is inactivated by oxygen free radicals?
Which class of calcium channel blockers is associated with drugs ending in -dipine?
Which class of calcium channel blockers is associated with drugs ending in -dipine?
What is the approximate half-life of Amlodipine, a calcium channel blocker from the Dihydropyridine class?
What is the approximate half-life of Amlodipine, a calcium channel blocker from the Dihydropyridine class?
What is the primary mechanism of action of Ivabradine in treating stable angina?
What is the primary mechanism of action of Ivabradine in treating stable angina?
Why are β blockers not used in variant angina treatment?
Why are β blockers not used in variant angina treatment?
What is the adverse effect of blocking β2 receptors in smooth muscle?
What is the adverse effect of blocking β2 receptors in smooth muscle?
How does Ranolazine primarily reduce O2 demand in heart muscle?
How does Ranolazine primarily reduce O2 demand in heart muscle?
Which drug selectively reduces heart rate and is used for heart failure and stable angina?
Which drug selectively reduces heart rate and is used for heart failure and stable angina?
What is the main mechanism of action of β blockers like Propranolol in angina treatment?
What is the main mechanism of action of β blockers like Propranolol in angina treatment?
