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Questions and Answers
What triggers muscle contraction by binding to actin to form a cross-bridge?
What is the approximate percentage of total cardiac output supplied by the left and right coronary arteries?
How is the balance between oxygen supply and demand in a normal heart affected during exercise?
Which condition results from a complete block in a coronary artery?
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What characterizes Unstable Angina compared to Stable Angina?
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In Ischemic Heart Disease, what leads to the occurrence of Angina Pectoris?
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What is the duration of action of nitroglycerin?
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Which formulation of nitroglycerin is most suitable for long-term prophylaxis of anginal attacks?
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How does the translingual spray formulation of nitroglycerin bypass liver inactivation?
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Which condition is effectively treated with intravenous (IV) nitroglycerin?
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Why is the sublingual formulation of nitroglycerin preferred for terminating an ongoing anginal attack?
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What is the goal of therapies for variant angina (Prinzmetal's angina)?
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Which drug class can lead to vasospasm in patients with variant angina?
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What is the mechanism of action of organic nitrites & nitrates in treating angina?
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Why should organic nitrites & nitrates not be used together with Sildenafil (PDE5 inhibitor)?
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Which of the following is a side effect associated with Amyl Nitrite inhalation?
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What is the main mechanism of antianginal action for organic nitrites and nitrates?
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Which adverse effect is commonly associated with excessive vasodilation from nitrites and nitrates?
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How is tolerance to nitrates typically prevented?
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Which enzyme involved in the mechanism of antianginal action is inactivated by oxygen free radicals?
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Which class of calcium channel blockers is associated with drugs ending in -dipine?
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What is the approximate half-life of Amlodipine, a calcium channel blocker from the Dihydropyridine class?
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What is the primary mechanism of action of Ivabradine in treating stable angina?
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Why are β blockers not used in variant angina treatment?
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What is the adverse effect of blocking β2 receptors in smooth muscle?
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How does Ranolazine primarily reduce O2 demand in heart muscle?
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Which drug selectively reduces heart rate and is used for heart failure and stable angina?
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What is the main mechanism of action of β blockers like Propranolol in angina treatment?
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