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Questions and Answers
What is a first-line urate lowering agent?
What is a first-line urate lowering agent?
- Colchicine
- NSAID
- Allopurinol (correct)
- Probenecid
Which patients are candidates for prophylactic therapy with urate lowering agents?
Which patients are candidates for prophylactic therapy with urate lowering agents?
- Patients with no history of gout attacks
- Patients with recurrent attacks, tophi, CKD stage 2 or worse, or past urolithiasis (correct)
- Patients with recurrent attacks, tophi, CKD stage 1, and no history of urolithiasis
- Patients with acute gout flare only
How does allopurinol reduce serum uric acid concentrations?
How does allopurinol reduce serum uric acid concentrations?
- By promoting the formation of tophi
- By blocking the enzyme xanthine oxidase (correct)
- By increasing the production of uric acid
- By decreasing uric acid excretion
For which patients should urate lowering therapy (ULT) be continued even during acute flares?
For which patients should urate lowering therapy (ULT) be continued even during acute flares?
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What is the primary active metabolite of allopurinol?
What is the primary active metabolite of allopurinol?
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Which intervention is part of non-pharmacologic therapy for gout prophylaxis?
Which intervention is part of non-pharmacologic therapy for gout prophylaxis?
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What is NOT a recommended approach in the pharmacologic therapy for gout prophylaxis?
What is NOT a recommended approach in the pharmacologic therapy for gout prophylaxis?
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Which of the following is an alternative first-line uricosuric agent?
Which of the following is an alternative first-line uricosuric agent?
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What should patients do along with maintaining hydration and managing comorbidities for gout prophylaxis?
What should patients do along with maintaining hydration and managing comorbidities for gout prophylaxis?
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