Unsaturated Fatty Acids: Structure and Properties

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What is the characteristic of the double bonds in unsaturated fatty acids?

They are nearly always in the cis configuration

What is the effect of introducing a cis double bond in a fatty acid?

It causes the acid to bend or 'kink' at that position

What is the relationship between the number of double bonds and the melting point of a fatty acid?

The more double bonds, the lower the melting point

What is the characteristic of the length of the hydrocarbon tail and the melting point of a fatty acid?

As the length increases, the melting point increases

What is the role of α-Linolenic acid (plant omega-3) in the body?

It is a precursor of long-chain omega-3 polyunsaturated fatty acids

What is the central architectural feature of biological membranes?

A double layer of lipids

What is the primary function of bile acids in the intestine?

To emulsify dietary fats

What is the role of cholesterol in myelin sheath?

To provide insulation for efficient conduction of impulses

What is the precursor molecule for the synthesis of vitamin D and steroid hormones?

Cholesterol

What is the primary source of acetyl-CoA for cholesterol synthesis?

β-oxidation of fatty acids

What is the first step in the biosynthesis of cholesterol?

Biosynthesis of mevalonate

What is the target of statins in cholesterol synthesis?

HMG-CoA reductase

In which tissue are maximum amounts of glycolipids found?

Nervous tissue

What is the role of gangliosides in the body?

Receptor for certain toxins and pathogens

What is the origin of the five-carbon ring in prostaglandins?

Arachidonic acid

What is the effect of PGE and PGI on blood pressure?

Decrease peripheral resistance

Which of the following is a function of prostaglandins?

Inflammatory mediator

What is the origin of the name 'prostaglandin'?

Prostate gland

What serves as an intracellular second messenger system in cells?

Inositol triphosphate and diacyl glycerol

What is the primary function of sphingolipids in cells?

To anchor certain proteins to the cell

What is the characteristic of sphingolipids that distinguishes them from other membrane lipids?

They contain no glycerol

What is the characteristic of cerebrosides and globosides?

They have no charge at pH 7

What is the characteristic of gangliosides?

They have oligosaccharides as their polar head groups

What is the common component of sphingolipids?

Ceramide

What is the product of the phosphorylation and decarboxylation of mevalonate?

Isopentenyl diphosphate

What is the result of the condensation reaction between geranyl pyrophosphate and isopentenyl diphosphate?

Farnesyl diphosphate

What is the enzyme responsible for converting squalene to 2,3-oxidosqualene?

Squalene epoxidase

What is the immediate product of the cyclization of 2,3-oxidosqualene?

Lanosterol

Where does the formation of cholesterol from lanosterol take place?

Endoplasmic reticulum

What is the result of the condensation of two molecules of farnesyl diphosphate?

Squalene

Test your knowledge on the characteristics of unsaturated fatty acids, including their structure, double bonds, and melting point. Learn how the presence of double bonds affects the fatty acid molecule and its properties.

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