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Questions and Answers
What is the mechanism of action of Amphotericin B?
What is the mechanism of action of Amphotericin B?
- Inhibition of squalene oxidase
- Inhibition of fungal cell wall synthesis
- Formation of a complex with Ergosterol leading to cytoplasmic leakage (correct)
- Inhibition of the enzyme 1,3 D-glucan synthase
Which of the following anti-fungal agents inhibits the fungal cytochrome p450 3A –dependent C 14demethylase?
Which of the following anti-fungal agents inhibits the fungal cytochrome p450 3A –dependent C 14demethylase?
- Caspofungin (correct)
- Amphotericin B
- Griseofulvin
- Flucytosine
How do Glucan synthesis Inhibitors act as anti-fungal agents?
How do Glucan synthesis Inhibitors act as anti-fungal agents?
- Inhibition of the enzyme 1,3 D-glucan synthase (correct)
- Inhibition of fungal cell wall synthesis
- Inhibition of fungal mitotic spindles
- Inhibition of ergosterol synthesis through the inhibition of squalene oxidase
Which anti-fungal agent primarily acts as a topical agent and inhibits ergosterol synthesis through the inhibition of squalene oxidase?
Which anti-fungal agent primarily acts as a topical agent and inhibits ergosterol synthesis through the inhibition of squalene oxidase?
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Which type of anti-fungal agent disrupts fungal cell mitotic spindles thus preventing fungal cell division?
Which type of anti-fungal agent disrupts fungal cell mitotic spindles thus preventing fungal cell division?
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What is the major lipid component of the fungal membrane that forms a complex with Amphotericin B?
What is the major lipid component of the fungal membrane that forms a complex with Amphotericin B?
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