PCO 401 Dr S S Agboola: Anti-fungal Agents Outlines

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20 Questions

Fungi are ______ organisms that live as saprobes or parasites.

eukaryotic

Fungal infections are also known as ______.

mycoses

Fungal cell wall is composed of ______.

chitin

Fungal cell membrane contains ______.

ergosterol

Fungal infections may be clinically classified as Superficial mycosis and ______ mycosis.

Deep (Systemic)

Polyene antibiotics act by binding to ______ in the fungal cell membrane.

sterol

Amphotericin B is a macrolide antibiotic with a large ______ ring.

lactone

Amphotericin B interacts hydrophobically with ______ in the fungal cell membrane forming a pore.

ergosterol

Liposomal preparations of amphotericin B have been developed to reduce ______ toxicity.

nephrotoxicity

Nystatin is too toxic for ______ use.

systemic

Amphotericin B is a ______ antibiotic with a large lactone ring.

macrolide

Polyene antibiotics act by binding to ______ in the fungal cell membrane.

sterol

Liposomal preparations of amphotericin B have been developed to reduce ______ toxicity.

nephrotoxicity

Fungal cell membrane contains ______.

ergosterol

Fungal infections may be clinically classified as Superficial mycosis and ______ mycosis.

deep

Fungi are ______ organisms that live as saprobes or parasites.

eukaryotic

Fungi have a rigid cell wall composed of ______.

chitin (N – acetylglucosamine)

Fungal cell membrane contains ______.

ergosterol

Fungi may be clinically classified as Superficial mycosis and ______ mycosis.

Deep (Systemic)

Yeast species include Blastomyces, candida, histoplasma, coccidioides, and ______.

cryptococcus

Explore the outlines of anti-fungal agents in PCO 401 with Dr S S Agboola. This quiz covers the classification, mode of action (MOA), indications, and adverse effects of anti-fungal agents, providing a comprehensive understanding of the topic.

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