PCO 401 Dr S S Agboola: Anti-fungal Agents Outlines
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PCO 401 Dr S S Agboola: Anti-fungal Agents Outlines

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Questions and Answers

Fungi are ______ organisms that live as saprobes or parasites.

eukaryotic

Fungal infections are also known as ______.

mycoses

Fungal cell wall is composed of ______.

chitin

Fungal cell membrane contains ______.

<p>ergosterol</p> Signup and view all the answers

Fungal infections may be clinically classified as Superficial mycosis and ______ mycosis.

<p>Deep (Systemic)</p> Signup and view all the answers

Polyene antibiotics act by binding to ______ in the fungal cell membrane.

<p>sterol</p> Signup and view all the answers

Amphotericin B is a macrolide antibiotic with a large ______ ring.

<p>lactone</p> Signup and view all the answers

Amphotericin B interacts hydrophobically with ______ in the fungal cell membrane forming a pore.

<p>ergosterol</p> Signup and view all the answers

Liposomal preparations of amphotericin B have been developed to reduce ______ toxicity.

<p>nephrotoxicity</p> Signup and view all the answers

Nystatin is too toxic for ______ use.

<p>systemic</p> Signup and view all the answers

Amphotericin B is a ______ antibiotic with a large lactone ring.

<p>macrolide</p> Signup and view all the answers

Polyene antibiotics act by binding to ______ in the fungal cell membrane.

<p>sterol</p> Signup and view all the answers

Liposomal preparations of amphotericin B have been developed to reduce ______ toxicity.

<p>nephrotoxicity</p> Signup and view all the answers

Fungal cell membrane contains ______.

<p>ergosterol</p> Signup and view all the answers

Fungal infections may be clinically classified as Superficial mycosis and ______ mycosis.

<p>deep</p> Signup and view all the answers

Fungi are ______ organisms that live as saprobes or parasites.

<p>eukaryotic</p> Signup and view all the answers

Fungi have a rigid cell wall composed of ______.

<p>chitin (N – acetylglucosamine)</p> Signup and view all the answers

Fungal cell membrane contains ______.

<p>ergosterol</p> Signup and view all the answers

Fungi may be clinically classified as Superficial mycosis and ______ mycosis.

<p>Deep (Systemic)</p> Signup and view all the answers

Yeast species include Blastomyces, candida, histoplasma, coccidioides, and ______.

<p>cryptococcus</p> Signup and view all the answers

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