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Questions and Answers
What is another name for acanthocytes?
Which type of red blood cell is pear-shaped?
What characteristic best describes schistocytes?
Which of the following is NOT a type of abnormal red blood cell listed?
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What associated condition is linked with abnormal red blood cells?
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Which of the following describes ovalocytes?
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Which type of abnormal red blood cell has a regularly spiculated surface?
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What characteristic is associated with echinocytes?
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Which symptom is NOT mentioned as being associated with abnormal red blood cells?
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What shape characterizes a drepanocyte?
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Which condition is frequently associated with the presence of bite cells?
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What is a common description for lepcocytes?
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Which of the following is a characteristic of biscuit cells?
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Which diagnostic test is used to identify disseminated intravascular coagulation (DIC)?
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What abnormal blood cell shape is associated with malaria?
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Which of the following cell types is commonly referred to as a 'target cell'?
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What are the shape characteristics of a semicircular body?
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Which statement best describes the potential conditions related to biscuity cells?
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In relation to other blood conditions, which condition is specifically linked with the over-activation of the coagulation cascade?
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Study Notes
Types of Abnormal Red Blood Cells (RBCs)
- Acanthocytes are also called thorny cells or spiculated cells.
- Burr cells are also known as echinocytes.
- Ovalocytes are similar in shape to an oval.
- Elliptocytes are elongated or oval-shaped.
- Dacryocytes are pear-shaped or teardrop-shaped.
- Schistocytes are fragmented RBCs.
- There are RBCs with irregularly spiculated surfaces.
- There are RBCs with regularly spiculated surfaces.
Associated Conditions
- Conditions associated with abnormal RBCs include thrombotic thrombocytopenic purpura (TTP) and Hemolytic Uremic Syndrome (HUS)
- These conditions can present with edema, abnormal blood chemistries, and unusual blood cell counts.
Blood Cell Morphology
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DREPANOCYTE (Sickle Cell): Sickle or crescent shaped. Two forms, Irreversible Sickle Cell (ISC)
- Conditions: Sickle cell anemia, Hemoglobin SC disease
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LEPTOCYTE: Codocytes, Platycytes. Greek helmet cell, Mexican hot cell, bull’s eye cell, target cell.
- Conditions: Liver disease, certain hemoglobinopathies, thalassemia, Mediterranean anemia
- BISCUIT CELL: Pronounced projections.
- BRONZE ELLIPTOCYTE: Elliptical-shaped cells.
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SEMILUNAR BODY: Semicircular with a bite mark.
- Conditions: Frequently seen in malaria and other conditions causing overt hemolysis
- BITE CELL: Demonstrates a semicircular edge (like a bite mark).
Blood Conditions and Markers
-
Disseminated Intravascular Coagulation (DIC): Defibrination syndrome, generalized over-activation of the coagulation cascade.
- Causes: Tissue trauma, obstetric complications, mucus-secreting tumors, infections (e.g., malaria, certain septicemia), acute promyelocytic leukemia
- Diagnostic Tests: D-dimer test, PF1+2 (Prothrombin Fragment 1 plus 2)
Frequently Seen Blood Cells
- Sickle Cells: Associated with Sickle Cell Anemia.
- Other Cells: Related to specific conditions such as DIC, and other blood-related disorders, including malaria.
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Description
This quiz explores various types of abnormal red blood cells (RBCs) such as acanthocytes and schistocytes. Additionally, it discusses associated conditions like thrombotic thrombocytopenic purpura and Hemolytic Uremic Syndrome. Test your knowledge on the characteristics and implications of these abnormalities.
