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Types and Causes of Primary and Secondary Immunodeficiency, Hypersensitivity Reactions

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Types and Causes of Primary and Secondary Immunodeficiency, Hypersensitivity Reactions

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Questions and Answers

Which of the following is NOT a characteristic of type III hypersensitivity reactions?

Immune complex deposition and tissue damage
Involvement of endogenous or exogenous antigens
Antigen-antibody complexes formed in the circulation
Immediate inflammatory response upon antigen exposure (correct)

In myasthenia gravis, which of the following mechanisms is responsible for the muscle weakness observed?

Antibodies against skeletal muscle cells directly cause muscle injury
Antibodies against acetylcholine receptors inhibit neuromuscular transmission (correct)
Cytokines produced by T cells induce chronic inflammation and muscle damage
Antibodies against acetylcholine receptors cause excessive stimulation of skeletal muscles

Which of the following is NOT an example of type II hypersensitivity disorders?

Autoimmune hemolytic anemia
Delayed-type hypersensitivity (DTH) reactions (correct)
Transfusion reactions
Hemolytic disease of the newborn

In Graves' disease, which of the following mechanisms is responsible for the hyperthyroidism observed?

Antibodies against thyroid-stimulating hormone receptor stimulate excessive thyroid hormone secretion (D) Signup and view all the answers

Which of the following is a characteristic of type IV hypersensitivity reactions?

Cytokine production by CD4+ T cells inducing chronic inflammation (A) Signup and view all the answers

In autoimmune hemolytic anemia, which of the following mechanisms is involved?

Antibodies against red blood cell antigens cause cell destruction (A) Signup and view all the answers

Which of the following is NOT a characteristic of delayed-type hypersensitivity (DTH) reactions?

Immediate inflammatory response upon antigen exposure (D) Signup and view all the answers

In certain drug reactions, which of the following mechanisms is involved?

Antibodies are produced against the drug-protein complex on red blood cells (A) Signup and view all the answers

Which of the following is NOT a characteristic of type II hypersensitivity disorders?

Immune complex deposition and complement activation (B) Signup and view all the answers

In hemolytic disease of the newborn, which of the following mechanisms is involved?

Maternal antibodies cross the placenta and cause destruction of fetal red blood cells (C) Signup and view all the answers