Immunodeficiency and Autoimmune Oral Health

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Questions and Answers

What type of hypersensitivity is a periodontal infection in a patient with immunodeficiency an example of?

  • Type III - Immune complex mediated hypersensitivity
  • Type I - Anaphylaxis
  • Type II - Antibody mediated hypersensitivity
  • Type IV - Delayed (cell-mediated) hypersensitivity (correct)

Which of the following oral manifestations is NOT commonly associated with immunodeficiency?

  • Severe tooth decay (caries) (correct)
  • Persistent ulcers
  • Candidiasis (thrush)
  • Recurrent herpes simplex infections

Which autoimmune disease is NOT typically associated with oral manifestations?

  • Psoriasis
  • Systemic Lupus Erythematosus
  • Crohn's disease (correct)
  • Scleroderma

Based on the information provided, which of these is the most likely reason why women of childbearing age are most often affected by autoimmune diseases?

<p>Hormonal fluctuations associated with pregnancy and menstruation may trigger autoimmune responses. (C)</p> Signup and view all the answers

Which of these treatment modalities is NOT generally used to manage autoimmune diseases?

<p>Antibiotics (A)</p> Signup and view all the answers

Flashcards

Immunodeficiency

Immune system dysfunction leading to recurrent infections and increased susceptibility to disease.

Type I Hypersensitivity (Anaphylaxis)

A type of hypersensitivity reaction characterized by an immediate and severe response to an allergen, often involving the release of histamine and other inflammatory mediators.

Autoimmune Disease

A type of hypersensitivity reaction where the immune system mistakenly attacks the body's own tissues and organs.

Type IV Hypersensitivity (Delayed-type hypersensitivity)

A type of hypersensitivity reaction that involves delayed cell-mediated immune responses to antigens. The reaction usually occurs 24-72 hours after exposure.

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Autoimmune Response

Antibodies produced by the immune system mistakenly target and attack the body's own tissues. This can lead to inflammation and damage.

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Study Notes

Immunodeficiency Oral Manifestations

  • Five oral manifestations: ulcers (recurrent/persistent), candidiasis, periodontitis, poor healing, herpes simplex virus

Autoimmune Conditions with Oral Manifestations

  • Four conditions: lichen planus, diabetes, systemic lupus erythematosus, pemphigus vulgaris

Hypersensitivity Types

  • Four types:
    • Type I: anaphylaxis
    • Type II: antibody-mediated
    • Type III: immune complex-mediated
    • Type IV: delayed (cell-mediated)

Penicillin Allergy Hypersensitivity Type

  • Type I (anaphylaxis)

Delayed Hypersensitivity in Dental Nurse

  • Type IV (delayed cell-mediated)

Autoimmune Diseases

  • Examples: rheumatoid arthritis, psoriasis

Autoimmune Disease Mechanism

  • Immune system mistakenly attacks the body's tissues

Autoimmune Disease Predominance

  • Women of childbearing age

Autoimmune Disease Treatment Exclusion

  • Type I diabetes (not treated with immunosuppressants)

Autoimmune Disease Impact on Organs

  • Skin, joints, and kidneys can be affected

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