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Treatment Options for Benign Prostatic Hyperplasia (BPH)

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32 Questions

What is the recommended management strategy for patients with mild symptoms of LUTS secondary to BPH?

Watchful Waiting

Which medication should be used with caution if the postvoid residual urine volume is > 100 to 150 mL to minimize the risk of acute urinary retention?

Urinary Anticholinergics

What is a characteristic of 5 Alpha Reductase Inhibitors (5ARIs) efficacy in the treatment of BPH?

Greater efficacy in those with large prostates

Which medication can exacerbate BPH symptoms by increasing urinary frequency?

Testosterone

What is the typical onset of action for Watchful Waiting in managing mild BPH symptoms?

6 months or more

What is a recommended non-pharmacological alternative for patients with moderate to severe signs and symptoms of BPH?

Educating the patient to take time to empty their bladder completely

Which class of medications may worsen BPH symptoms by decreasing the ability of the bladder to contract and force urine out?

Antihistamines

What is the impact of anticholinergics on patients with BPH?

Decrease the ability of the bladder to contract

What is a common lifestyle modification recommended for patients with BPH?

Limiting fluid intake close to bedtime

Which type of medication may be used in patients with BPH who have irritative symptoms?

Tricyclic antidepressants

Which of the following complications is NOT associated with Benign Prostatic Hyperplasia (BPH)?

Acute respiratory distress syndrome (ARDS)

What is considered a clinically significant change in the AUA-SI for BPH?

AUA-SI decrease of 3 points

In BPH management, what is the goal of therapy related to lower urinary tract symptoms?

Reduce bothersome LUTS

How are BPH patients classified based on bothersome symptoms and/or severity?

Based on AUA-SI score

What is the recommended management strategy for BPH patients under 'Watchful Waiting'?

Regular monitoring without pharmacological or surgical management

Which of the following complications is associated with Benign Prostatic Hyperplasia (BPH)?

Anemia

What is a key aspect of the evaluation and assessment of Benign Prostatic Hyperplasia (BPH)?

Performing a rectal examination

What is one of the primary goals of therapy in Benign Prostatic Hyperplasia (BPH)?

Relieving lower urinary tract symptoms

How can Benign Prostatic Hyperplasia (BPH) impact a patient's quality of life?

Causing sexual dysfunction

Which of the following is a common sign or symptom of Benign Prostatic Hyperplasia (BPH)?

Urinary frequency and urgency

What is the recommended dosing for Tadalafil (Cialis) in patients with BPH?

5mg tablet daily

Which combination therapy for BPH does the AUA 2021 guidelines mention as not offering advantages in symptom improvement?

Tadalafil and α1 antagonist

In patients with BPH and ED, what could be considered as an alternative treatment option according to the provided information?

PDE5I

What is the recommended dose adjustment for Tadalafil when a patient is using strong CYP3A4 Inhibitors?

Decrease the dose to 2.5mg daily

What is the impact of PDE5Is on patients with BPH and ED compared to α1 adrenergic antagonists?

Slower onset of action

Which selective Alpha 1a blocker has an ER formulation that behaves like a Uroselective a1A?

Alfuzosin (uroxatral)

Which Non selective(uroselective) not recommened by the AUA

Prazosin (minipress)

Two common Selective a1a antagonist

tamsulosin (flomax) & Silodosin (rapaflo)

a1A do reduce the prostate size and don't offer prevention for progression of BPH or the need for surgery

False

False

a1A blockers work faster than 5a reductase inhibitors (5ARI)

True

What two a1A blockers is required to be given at night

Doxazosin and Terazosin

Learn about the various treatment options available for patients with Benign Prostatic Hyperplasia (BPH), including alpha adrenergic antagonists, 5 alpha reductase inhibitors, phosphodiesterase 5 inhibitors, and antimuscarinics or B3 agonists. Explore pharmacological and non-pharmacological alternatives for managing BPH symptoms.

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