Treatment Options for Benign Prostatic Hyperplasia (BPH)

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What is the recommended management strategy for patients with mild symptoms of LUTS secondary to BPH?

Starting 5 Alpha Reductase Inhibitors right away
Watchful Waiting (correct)
Immediate surgical intervention
Avoiding all medications including alpha blockers

Which medication should be used with caution if the postvoid residual urine volume is > 100 to 150 mL to minimize the risk of acute urinary retention?

Urinary Anticholinergics (correct)
Testosterone
Diuretics
5 Alpha Reductase Inhibitors

What is a characteristic of 5 Alpha Reductase Inhibitors (5ARIs) efficacy in the treatment of BPH?

Greater efficacy in those with large prostates (correct)
Rapid onset of action within days
Most effective in patients with small prostates
Effective for reducing prostate volume in all patients

Which medication can exacerbate BPH symptoms by increasing urinary frequency?

Testosterone (D) Signup and view all the answers

What is the typical onset of action for Watchful Waiting in managing mild BPH symptoms?

6 months or more (D) Signup and view all the answers

What is a recommended non-pharmacological alternative for patients with moderate to severe signs and symptoms of BPH?

Educating the patient to take time to empty their bladder completely (D) Signup and view all the answers

Which class of medications may worsen BPH symptoms by decreasing the ability of the bladder to contract and force urine out?

Antihistamines (C) Signup and view all the answers

What is the impact of anticholinergics on patients with BPH?

Decrease the ability of the bladder to contract (C) Signup and view all the answers

What is a common lifestyle modification recommended for patients with BPH?

Limiting fluid intake close to bedtime (B) Signup and view all the answers

Which type of medication may be used in patients with BPH who have irritative symptoms?

Tricyclic antidepressants (A) Signup and view all the answers

Which of the following complications is NOT associated with Benign Prostatic Hyperplasia (BPH)?

Acute respiratory distress syndrome (ARDS) (D) Signup and view all the answers

What is considered a clinically significant change in the AUA-SI for BPH?

AUA-SI decrease of 3 points (C) Signup and view all the answers

In BPH management, what is the goal of therapy related to lower urinary tract symptoms?

Reduce bothersome LUTS (D) Signup and view all the answers

How are BPH patients classified based on bothersome symptoms and/or severity?

Based on AUA-SI score (B) Signup and view all the answers

What is the recommended management strategy for BPH patients under 'Watchful Waiting'?

Regular monitoring without pharmacological or surgical management (C) Signup and view all the answers

Which of the following complications is associated with Benign Prostatic Hyperplasia (BPH)?

Anemia (A) Signup and view all the answers

What is a key aspect of the evaluation and assessment of Benign Prostatic Hyperplasia (BPH)?

Performing a rectal examination (B) Signup and view all the answers

What is one of the primary goals of therapy in Benign Prostatic Hyperplasia (BPH)?

Relieving lower urinary tract symptoms (C) Signup and view all the answers

How can Benign Prostatic Hyperplasia (BPH) impact a patient's quality of life?

Causing sexual dysfunction (B) Signup and view all the answers

Which of the following is a common sign or symptom of Benign Prostatic Hyperplasia (BPH)?

Urinary frequency and urgency (B) Signup and view all the answers

What is the recommended dosing for Tadalafil (Cialis) in patients with BPH?

5mg tablet daily (B) Signup and view all the answers

Which combination therapy for BPH does the AUA 2021 guidelines mention as not offering advantages in symptom improvement?

Tadalafil and α1 antagonist (A) Signup and view all the answers

In patients with BPH and ED, what could be considered as an alternative treatment option according to the provided information?

PDE5I (D) Signup and view all the answers

What is the recommended dose adjustment for Tadalafil when a patient is using strong CYP3A4 Inhibitors?

Decrease the dose to 2.5mg daily (C) Signup and view all the answers

What is the impact of PDE5Is on patients with BPH and ED compared to α1 adrenergic antagonists?

Slower onset of action (A) Signup and view all the answers

Which selective Alpha 1a blocker has an ER formulation that behaves like a Uroselective a1A?

Alfuzosin (uroxatral) (A) Signup and view all the answers

Which Non selective(uroselective) not recommened by the AUA

Prazosin (minipress) (D) Signup and view all the answers

Two common Selective a1a antagonist

tamsulosin (flomax) & Silodosin (rapaflo) (A) Signup and view all the answers

a1A do reduce the prostate size and don't offer prevention for progression of BPH or the need for surgery

False (B) Signup and view all the answers

a1A blockers work faster than 5a reductase inhibitors (5ARI)

True (A) Signup and view all the answers

What two a1A blockers is required to be given at night

Doxazosin and Terazosin (A) Signup and view all the answers

Management for mild LUTS from BPH

Watchful waiting is the recommended initial approach for patients with mild lower urinary tract symptoms (LUTS) due to benign prostatic hyperplasia (BPH).

Caution with anticholinergics in BPH

If post-void residual urine volume is greater than 100-150ml, use urinary anticholinergics cautiously to prevent potential acute urinary retention.

5-ARIs efficacy in BPH

5-alpha reductase inhibitors (5ARIs) are more effective in treating BPH in patients who have larger prostates.

BPH symptom worsening medication

Testosterone can exacerbate benign prostatic hyperplasia (BPH) symptoms by increasing urinary frequency.