Benign Prostatic Hyperplasia Treatment Overview
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Questions and Answers

How often do patients with BPH managed via watchful waiting need to return for monitoring?

  • Monthly
  • 6-to-12 months intervals (correct)
  • Every 2 years
  • Weekly

    • Which type of medication is used to relax the bladder detrusor muscle in BPH?

  • Anticholinergics (correct)
  • Phosphodiesterase inhibitors
  • 5-alpha reductase inhibitors
  • Alpha-1 antagonists

    • What do selective Alpha-1 antagonists specifically target in the body?

  • Bladder tissue
  • Prostate tissue (correct)
  • Kidney tissue
  • Liver tissue

    • What is the recommended initial dosing strategy for non-selective Alpha-1 antagonists to avoid potential side effects?

    <p>Slow titration over several weeks</p> Signup and view all the answers

    Why is Tamsulosin considered a good first-line option for BPH treatment?

    <p>It is cheap and effective at decreasing AUA scores</p> Signup and view all the answers

    What is the primary goal of treatment for BPH?

    <p>Decrease AUA score by at least three points</p> Signup and view all the answers

    Why are pharmaceuticals used in the treatment of BPH?

    <p>To delay the need for surgical intervention</p> Signup and view all the answers

    What is a characteristic of non-selective Alpha-1 antagonists in terms of initial dosing?

    <p>May cause first-dose syncope and dizziness</p> Signup and view all the answers

    How do selective Alpha-1 antagonists differ from non-selective Alpha-1 antagonists?

    <p>They do not require dose titration</p> Signup and view all the answers

    Which medication should not be used in patients with severe liver dysfunction or creatinine clearance less than 30 ml/min?

    <p>Silodosin</p> Signup and view all the answers

    Alpha-1 Antagonists do not prevent the need for prostate surgery, decrease prostate size, or decrease PSA levels

    <p>True</p> Signup and view all the answers

    What is the mechanism of action of Alpha-1 antagonists in the treatment of BPH?

    <p>Relaxing prostate smooth muscle to improve urine flow</p> Signup and view all the answers

    Which type of Alpha-1 antagonist can be used in patients with cardiovascular disease?

    <p>Selective Alpha-1 Antagonists</p> Signup and view all the answers

    Why are non-selective alpha-1 antagonists not recommended as a single medication for treating BPH and hypertension?

    <p>They can increase the risk of hypotension</p> Signup and view all the answers

    Which Alpha-1 antagonist does not need dose adjustments based on renal or liver dysfunction?

    <p>Tamsulosin</p> Signup and view all the answers

    What is a notable side effect associated with selective Alpha-1 antagonists?

    <p>Floppy iris syndrome</p> Signup and view all the answers

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