16 Questions
How often do patients with BPH managed via watchful waiting need to return for monitoring?
6-to-12 months intervals
Which type of medication is used to relax the bladder detrusor muscle in BPH?
Anticholinergics
What do selective Alpha-1 antagonists specifically target in the body?
Prostate tissue
What is the recommended initial dosing strategy for non-selective Alpha-1 antagonists to avoid potential side effects?
Slow titration over several weeks
Why is Tamsulosin considered a good first-line option for BPH treatment?
It is cheap and effective at decreasing AUA scores
What is the primary goal of treatment for BPH?
Decrease AUA score by at least three points
Why are pharmaceuticals used in the treatment of BPH?
To delay the need for surgical intervention
What is a characteristic of non-selective Alpha-1 antagonists in terms of initial dosing?
May cause first-dose syncope and dizziness
How do selective Alpha-1 antagonists differ from non-selective Alpha-1 antagonists?
They do not require dose titration
Which medication should not be used in patients with severe liver dysfunction or creatinine clearance less than 30 ml/min?
Silodosin
Alpha-1 Antagonists do not prevent the need for prostate surgery, decrease prostate size, or decrease PSA levels
True
What is the mechanism of action of Alpha-1 antagonists in the treatment of BPH?
Relaxing prostate smooth muscle to improve urine flow
Which type of Alpha-1 antagonist can be used in patients with cardiovascular disease?
Selective Alpha-1 Antagonists
Why are non-selective alpha-1 antagonists not recommended as a single medication for treating BPH and hypertension?
They can increase the risk of hypotension
Which Alpha-1 antagonist does not need dose adjustments based on renal or liver dysfunction?
Tamsulosin
What is a notable side effect associated with selective Alpha-1 antagonists?
Floppy iris syndrome
Learn about the goals of treatment for Benign Prostatic Hyperplasia (BPH), including symptom reduction and improvement of urinary flow rate. Explore pharmaceutical and non-pharmaceutical treatment options to manage BPH effectively.
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