Benign Prostatic Hyperplasia Treatment Overview
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Questions and Answers

How often do patients with BPH managed via watchful waiting need to return for monitoring?

  • Monthly
  • 6-to-12 months intervals (correct)
  • Every 2 years
  • Weekly

Which type of medication is used to relax the bladder detrusor muscle in BPH?

  • Anticholinergics (correct)
  • Phosphodiesterase inhibitors
  • 5-alpha reductase inhibitors
  • Alpha-1 antagonists

What do selective Alpha-1 antagonists specifically target in the body?

  • Bladder tissue
  • Prostate tissue (correct)
  • Kidney tissue
  • Liver tissue

What is the recommended initial dosing strategy for non-selective Alpha-1 antagonists to avoid potential side effects?

<p>Slow titration over several weeks (C)</p> Signup and view all the answers

Why is Tamsulosin considered a good first-line option for BPH treatment?

<p>It is cheap and effective at decreasing AUA scores (C)</p> Signup and view all the answers

What is the primary goal of treatment for BPH?

<p>Decrease AUA score by at least three points (D)</p> Signup and view all the answers

Why are pharmaceuticals used in the treatment of BPH?

<p>To delay the need for surgical intervention (D)</p> Signup and view all the answers

What is a characteristic of non-selective Alpha-1 antagonists in terms of initial dosing?

<p>May cause first-dose syncope and dizziness (C)</p> Signup and view all the answers

How do selective Alpha-1 antagonists differ from non-selective Alpha-1 antagonists?

<p>They do not require dose titration (B)</p> Signup and view all the answers

Which medication should not be used in patients with severe liver dysfunction or creatinine clearance less than 30 ml/min?

<p>Silodosin (A)</p> Signup and view all the answers

Alpha-1 Antagonists do not prevent the need for prostate surgery, decrease prostate size, or decrease PSA levels

<p>True (A)</p> Signup and view all the answers

What is the mechanism of action of Alpha-1 antagonists in the treatment of BPH?

<p>Relaxing prostate smooth muscle to improve urine flow (B)</p> Signup and view all the answers

Which type of Alpha-1 antagonist can be used in patients with cardiovascular disease?

<p>Selective Alpha-1 Antagonists (B)</p> Signup and view all the answers

Why are non-selective alpha-1 antagonists not recommended as a single medication for treating BPH and hypertension?

<p>They can increase the risk of hypotension (C)</p> Signup and view all the answers

Which Alpha-1 antagonist does not need dose adjustments based on renal or liver dysfunction?

<p>Tamsulosin (B)</p> Signup and view all the answers

What is a notable side effect associated with selective Alpha-1 antagonists?

<p>Floppy iris syndrome (A)</p> Signup and view all the answers

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