212B Male Reproductive BPH Overview

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Questions and Answers

What is a common symptom associated with BPH?

  • Severe back pain
  • Rapid weight gain
  • Frequent need to urinate (correct)
  • Increased appetite

TURP is a surgery that reduces the size of the prostate.

True (A)

Name one peripherally acting alpha-adrenergic blocker used in the treatment of BPH.

Tamsulosin

The increase in prostate cell growth is primarily ____________ sensitive.

<p>testosterone</p> Signup and view all the answers

Which of the following statements about 5-alpha-reductase inhibitors is true?

<p>They reduce the size of the prostate. (C)</p> Signup and view all the answers

What should be done before cataract surgery in patients taking alpha-adrenergic blockers?

<p>Hold the medication.</p> Signup and view all the answers

Match the drug with its effect or classification:

<p>Tamsulosin = Urinary flow symptoms associated with BPH Finasteride = Reduces size of the prostate DRE = Digital rectal exam for diagnosis PSA = Used to rule out prostate cancer</p> Signup and view all the answers

Patients on 5-alpha-reductase inhibitors can donate blood immediately after their last dose.

<p>False (B)</p> Signup and view all the answers

Flashcards

BPH

Benign prostatic hyperplasia, a non-cancerous enlargement of the prostate gland that occurs with aging, often affecting men over 80.

BPH Symptoms

Frequent urination, small urine volume, incomplete bladder emptying.

BPH Cause

Excessive growth of prostate cells, primarily driven by testosterone.

BPH Diagnosis

Digital rectal exam (DRE) to assess prostate size and PSA test to rule out cancer.

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Peripherally Acting Alpha-Adrenergic Blockers

Medications that relax the prostate muscles, improving urine flow by blocking alpha receptors in the prostate.

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5-Alpha-Reductase Inhibitors

Drugs that reduce the size of the prostate by inhibiting the enzyme that converts testosterone to a form that stimulates prostate growth.

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TURP

Transurethral resection of the prostate, surgical removal of prostate tissue to improve urine flow.

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TUNA

Transurethral needle ablation, a minimally invasive technique using heat to destroy excess prostate tissue.

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Study Notes

Male Reproductive (BPH)

  • Benign Prostatic Hyperplasia (BPH) is excessive prostate cell growth
  • Primarily occurs in men aged 80 and older (80% prevalence)
  • Prostate growth is testosterone-sensitive
  • The enlarged prostate presses on the urethra, hindering urine flow

Symptoms (S/S)

  • Frequent urination
  • Small urine volume
  • Difficulty emptying the bladder completely

Diagnosis

  • Digital Rectal Exam (DRE)
  • Prostate-Specific Antigen (PSA) test to rule out cancer

Treatments

  • Transurethral Needle Ablation (TUNA): A needle ablation procedure
  • Transurethral Resection of the Prostate (TURP): Most common surgical procedure, involves cutting/removing prostate tissue with a catheter and irrigation afterwards.
  • Transurethral Incision of the Prostate (TUIP): Incision of the prostate using a catheter
  • Three way catheter is used after TURP surgery. The catheter constantly irrigates the area.

Medications (Classification)

  • Peripherally Acting Alpha Adrenergic Blockers: These medications block receptors in the prostate, relaxing the prostate tissue

    • Examples include Tamsulosin (Flomax).
    • Side effects: headache, fatigue, dizziness, lethargy, tachycardia, hypotension, sexual dysfunction; should be held before surgery.

  • 5-alpha-Reductase Inhibitors/Androgen Inhibitors: These medications inhibit the enzymes that convert testosterone into a form that enlarges the prostate. This reduces prostate size.

    • Example: Finasteride (Proscar).
    • Side effect: Cannot donate blood for 6 months after using this medication

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