Tranexamic Acid (TXA) in Traumatic Bleeding
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Questions and Answers

What is the mechanism of action of Tranexamic Acid?

  • It increases plasmin formation
  • It stabilizes fibrinogen and decreases plasmin formation (correct)
  • It destabilizes fibrinogen and increases plasmin formation
  • It reduces blood clotting

Which of the following is not an indication for the use of Tranexamic Acid?

  • Patient Condition c/w hemorrhagic shock or TBI
  • Anticoagulation medications such as Coumadin, Pradaxa, Xarelto, Eliquis, Edoxaban, Enoxaparin
  • Blunt or Penetrating Trauma
  • Injuries greater than 3 hours (correct)

How can Tranexamic Acid be administered?

  • Topically
  • Orally
  • Intramuscularly
  • Through IO or IV (correct)

What is the criteria for Traumatic Brain Injury for the use of Tranexamic Acid?

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