Title and Description Writing Quiz

Platelets release inflammatory mediators and platelet-derived growth factor (PDGF), which stimulate the migration and proliferation of smooth muscle cells (SMCs) in the arterial wall. This contributes to the formation of a fibrous plaque in the intima.

Platelets release inflammatory mediators and PDGF, which stimulate the migration and proliferation of SMCs, leading to the formation of fatty streaks.

Macrophages and SMCs ingest cholesterol and transform into foam cells, which accumulate to form fatty streaks in the arterial wall. These fatty streaks are the earliest visible lesion of atherosclerosis and can progress to form a fibrous plaque, leading to arterial stenosis.

<p>Macrophages and SMCs ingest cholesterol and transform into foam cells, which accumulate to form fatty streaks. Lipid-laden cells produce extracellular matrix, leading to the development of a fibrous plaque.</p> Signup and view all the answers

<p>Plaque rupture can lead to thrombus formation and vascular occlusion, which can cause myocardial infarction, stroke, or peripheral artery disease. This is because the thrombus can obstruct blood flow to vital organs or tissues, leading to tissue ischemia and damage.</p> Signup and view all the answers

<p>Plaque rupture can lead to thrombus formation and vascular occlusion, which can result in heart attack or stroke.</p> Signup and view all the answers